Impact of preoperative treatment on the CINSARC prognostic signature: translational research results from a  phase 1 trial of the German Interdisciplinary Sarcoma Group (GISG 03)

ConclusionConcurrent radiation therapy and sunitinib leads to diverging results of prognostic gene array testing in a  relevant proportion of sarcoma patients. These changes may reflect tumor heterogeneity, local treatment effects, or prognostic changes of the disease. Caution is advised in the selection of samples and interpretation of test results.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research