Traumatic Brain Injury Disrupts Cerebrovascular Tone Through Endothelial Inducible Nitric Oxide Synthase Expression and Nitric Oxide Gain of Function [Stroke]

Conclusions The mechanism of profound cerebral artery vasodilation after TBI is a gain of function in vascular NO production by 60-fold over controls, resulting from upregulation of the inducible isoform of NO synthase in the endothelium.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Tags: Stroke Source Type: research