Serum human epididymis protein 4 concentrations are associated with severity of patients with pulmonary tuberculosis

Publication date: Available online 12 November 2019Source: Clinica Chimica ActaAuthor(s): Laisheng Li, Yingsheng Yao, Jianbo Liang, Xiaoxia Zhan, Fen Wang, Caifeng Yue, Ben-Quan Wu, Shengfeng Hu, Min Liu, Jianxin Wan, Jinmei LuoAbstractBackgroundHuman epididymis protein 4 (HE4) has been recognized as a biomarker which elevated in various diseases. The aim of this study was to evaluate the value of serum HE4 in pulmonary tuberculosis (PTB).MethodsSerum HE4 concentrations were determined in 127 PTB, 88 chronic bronchitis (CHB), and 105 healthy control subjects by chemiluminescent microparticle immunoassay. Receiver operating characteristic (ROC) curves and Spearman's correlation analysis were performed for investigating value of HE4.ResultsSerum HE4 concentrations were significantly increased in PTB (62.8 pmol/L, IQR 45.8-90.7), compared with that of CHB (50.2 pmol/L, IQR 42.3-64.3, P=0.0002) and normal control (35.4 pmol/L, IQR 31.1-42.9, P
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research

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Dyspnea is the most important respiratory symptom. Objectivization of its severity is an important evaluation parameter of health condition.Objective: to evaluate the prevalence of respiratory symptoms in the rural population.Results: completed questionnaires 3621 resident, including the 1505 primary health care (PHC) based patients, and 2116 household based patients, living on the territory of the settlements included in the research. The age of the respondents is 53.7 ±1.0 years for PHC based patients and 49.9 ±1.6 years for household based patients. Male is accounted for 31.5% and 34.4% respectively in bot...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Abstract BACKGROUND: Human epididymis protein 4 (HE4) has been recognized as a biomarker which elevated in various diseases. The aim of this study was to evaluate the value of serum HE4 in pulmonary tuberculosis (PTB). METHODS: Serum HE4 concentrations were determined in 127 PTB, 88 chronic bronchitis (CHB), and 105 healthy control subjects by chemiluminescent microparticle immunoassay. Receiver operating characteristic (ROC) curves and Spearman's correlation analysis were performed for investigating value of HE4. RESULTS: Serum HE4 concentrations were significantly increased in PTB (62.8 pmol/L, IQR 45....
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Tags: Clin Chim Acta Source Type: research
CONCLUSIONS: Patients with a history of lung disease including chronic bronchitis, emphysema, tuberculosis, lung cancer and pneumonia, and a history of thoracic surgery, might have an increased post-acupuncture risk of pneumothorax. This information may possibly help physicians avoid post-acupuncture pneumothorax. PMID: 31433202 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - Category: Complementary Medicine Authors: Tags: Acupunct Med Source Type: research
There are several types of chest infections, including bronchitis, pneumonia, and tuberculosis. Learn more about the symptoms and treatment options in this article.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Publication date: Available online 20 June 2019Source: The LancetAuthor(s): Kewu Huang, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Guodong Xu, Sinan Wu, Chaolong Wang, Ruiying Wang, Zhihong ShiSummaryBackgroundAsthma is a common chronic airway disease worldwide. Despite its large population size, China has had no comprehensive study of the national prevalence, risk factors, and management of asthma. We therefore aimed to estimate the national prevalence of asthma in a representative s...
Source: The Lancet - Category: General Medicine Source Type: research
Conclusions: Workplace exposures contribute to the burden of disease across a range of nonmalignant lung conditions in adults (in addition to the 100% burden for the classic occupational pneumoconioses). This burden has important clinical, research, and policy implications. There is a pressing need to improve clinical recognition and public health awareness of the contribution of occupational factors across a range of nonmalignant respiratory diseases. PMID: 31149852 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Akshay Chandel, Amit K. Goyal, Goutam Ghosh, Goutam RathAbstractPulmonary route is extensively studied for the diagnosis and treatment of pulmonary and extra pulmonary disease conditions such as asthma, tuberculosis, emphysema, and bronchitis. Formulation design, inhalation device and particle size play key role in determining the aerosol performance. The lack of desired clinical outcome along with the problem regarding efficacy or any adverse drug effect may arise due to improper training and education in use of the device to contro...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Abstract Pulmonary route is extensively studied for the diagnosis and treatment of pulmonary and extra pulmonary disease conditions such as asthma, tuberculosis, emphysema, and bronchitis. Formulation design, inhalation device and particle size play key role in determining the aerosol performance. The lack of desired clinical outcome along with the problem regarding efficacy or any adverse drug effect may arise due to improper training and education in use of the device to control the actuation and aerosol inhalation. This review summarizes the difference in the mechanistic features of current marketed aerosol del...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
AbstractPaddy and wheat cropping is a widespread farming practice in northwestern parts of India, primarily in the riverine plains of Haryana and Punjab. These fertile lands are well known for extensive agricultural fields; however, they are equally infamous for the burning of paddy and wheat straw and stubble by farmers after the harvesting season. In India, it is reckoned that 22,289 gigagrams (Gg) of paddy stubble biomass is generated annually, and of this 13,915 Gg (62.42%) is set ablaze in the agricultural fields. Haryana and Punjab alone produce 48% of the whole straw production in India, which is openly burned in si...
Source: Environmental Quality Management - Category: Environmental Health Authors: Tags: RESEARCH ARTICLE Source Type: research
Conclusion: Male gender, family history of respiratory diseases and use of mosquito coil were significant predictors of respiratory symptoms. Awareness and education at community level may decrease the incidence and progression of respiratory symptoms to chronic disability.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Occupational and Environmental Health Source Type: research
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