Multiple myeloma: role of autologous transplantation
Multiple myeloma (MM) is an incurable plasma cell dyscrasia characterized by the uncontrollable proliferation of clonal plasma cells resulting in myeloma-defining events (end-organ damage and/or biomarkers of malignancy) [1]. MM constitutes a significant contributor to the global burden of hematological malignancy causing 2.1 million disability-adjusted life-years (DALYs) worldwide according to the Global Burden of Disease 2016 study [2]. During the last decades, an increase in the disease incidence has been clearly demonstrated, especially in North America, Western Europe and Australasia [2].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Efstathios Kastritis, Evangelos Terpos, Meletios A Dimopoulos Tags: Anti-Tumour Treatment Source Type: research