Non-functional paraganglioma of urinary bladder managed by transurethral resection
Conclusion Complete TURBT is a safe and efficient treatment that serves both diagnostic and therapeutic purposes. Histopathological and immunohistochemistry examinations are mandatory for diagnostic confirmation. Long-term follow-up is recommended for patients with non-functional PUB.
Among women with metastatic breast cancer, use of an investigational oral form of paclitaxel yielded a higher overall response rate than the IV form, but administration was unique and time-consuming.Medscape Medical News
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Jack Cuzick, Ivana Sestak, John F Forbes, Mitch Dowsett, Simon Cawthorn, Robert E Mansel, Sibylle Loibl, Bernardo Bonanni, D Gareth Evans, Anthony Howell, IBIS-II investigatorsSummaryBackgroundTwo large clinical trials have shown a reduced rate of breast cancer development in high-risk women in the initial 5 years of follow-up after use of aromatase inhibitors (MAP.3 and International Breast Cancer Intervention Study II [IBIS-II]). Here, we report blinded long-term follow-up results for the IBIS-II trial, which compared anastrozole with placebo...
ConclusionsMHSCC seems to show a better overall survival compared to OSCC of other locations and is less likely to develop regional and distant metastasis; END might not be necessary in early stage tumors.
CONCLUSION: NUBTs present with similar clinicoradiological findings; however, their histological features along with immunohistochemistry help in the definite diagnosis. One should be aware of these tumors as they frequently present diagnostic and therapeutic challenge. Most of these neoplasms present at an advanced stage. Large or multicentric randomized controlled studies are needed to know the exact behavior and prognosis of these tumors.
DiscussionIntravesical BCG is a standard adjuvant treatment for carcinoma in situ with 75% induced cystitis as a local side effect. The International Bladder Cancer Group’s recommendation for BCG cystitis included many agents, these treatment options had very limited outcomes. The existence of paraganglioma in the female genital tract described rarely
ConclusionsHere we report a rare case of paraganglioma in the bladder. We discuss paraganglioma based on previous studies.
Conclusions Preliminary data from this ongoing study shows that 18 F-MFBG imaging is safe, has favorable biodistribution and kinetics with good targeting of lesions. Imaging with 18 F-MFBG allows for same-day, quantitative imaging of NET with high-resolution using PET. Research support: Dept of Radiology Seed Grant, MSKCC; The MSKCC Radiochemistry &Molecular Imaging Probe Core, supported in part by NIH Cancer Center Support Grant P30CA008748-48. $$graphic_AFAFA95B-79A9-46B0-A0BD-4F11F4E377E7$$
Rashmi Patnayak, P Preetam, Amitabh Jena, Satyanarayana , S Subramanian, AY LakshmiJournal of Cancer Research and Therapeutics 2015 11(4):1039-1039Urinary bladder paragangliomas are rare with a reported incidence of
We present a case of an organ confined urinary bladder paraganglioma and concomitant metastatic lung cancer to the liver diagnosed on a 66 year old man initially though to be metastatic bladder cancer. The patient was referred to our hospital for frank hematuria and a single solid bladder tumor was identified at flexible cystoscopy. We are also reviewing the literature on the diagnostic and therapeutic approach of extra-adrenal phaeochromocytoma.
CONCLUSION: Current evidence supporting lymphadenectomy in the surgical management of bladder cancer is largely based on studies limited to urothelial cancer. Despite this the practice of lymphadenectomy in non-urothelial cancer is common. We support lymphadenectomy in non-urothelial bladder cancer given the minimal risk associated with the procedure and the potential for improved survival. PMID: 26684181 [PubMed - as supplied by publisher]