A Molecular Solution to the Opioid Epidemic A Molecular Solution to the Opioid Epidemic

If investigators can block the neurologic mechanism of opioid-induced respiratory depression, they might be able to develop an analgesic without the deadly adverse effect.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Related Links:

Authors: Shoib S, Kim YK Abstract Suicide is a serious public health problem in many countries and has always been a source of apprehension and quest to human mankind, which can be resolved with due diligence. Suicide is a hidden and silent epidemic, with many causative factors. Studying and researching on various causative factors have always been the subject of significance for the researchers. Psychiatric illnesses happen to be the primary reasons for the majority of suicide mortality cases. Not only this, there has been a consistent increase in the no. of cases of mental disorders as well as attempted and compl...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
But ERs say they lack the resources to screen patients for suicidal thoughts.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
More millennials in the U.S. are suffering from chronic health problems, potentially restraining the lifetime economic potential of a generation of young adults. A spike in conditions like depression, hypertension and high cholesterol among younger people could increase health-care costs and lower incomes in coming years, according to a report Wednesday from the Blue Cross Blue Shield Association, a federation of 36 independent companies that together provide coverage for 1 in 3 Americans. Between 2014 and 2017, rates of depression among millennials surged by 31%, while hyperactivity rose 29% and hypertension increased 16%...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Bloomberg Healthcare onetime Source Type: news
Regional and national newspapers in the United States are falling short of meeting guidelines for reporting on suicide deaths, suggests areport inJAMA Network Open. An analysis of coverage following the deaths of Kate Spade and Anthony Bourdain in June 2018 in print newspapers with a minimum circulation of 200,000 shows that the publications adhered to only about half of the national recommendations for reporting on suicide, such as avoiding details of lethal means or use of a sensational headline.“News media coverage of suicide is associated with an increased risk of subsequent suicides, with the strongest associati...
Source: Psychiatr News - Category: Psychiatry Tags: Anthony Bourdain Arielle H. Sheftall JAMA Network Open Kate Spade media newspaper Recommendations for Reporting on Suicide Source Type: research
k W. Dabney Early life stress (ELS) induced by psychological trauma, child maltreatment, maternal separation, and domestic violence predisposes to psycho-behavioral pathologies during adulthood, namely major depressive disorder (MDD), anxiety, and bipolar affective disorder. While environmental data are available in illustrating this association, data remain to be established on the epigenomic underpinning of the nexus between ELS and MDD predisposition. Specifically, despite the observed aberrant epigenomic modulation of the NR3C1, a glucocorticoid receptor gene, in early social adversity and social threats in animal ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
According to the Institute of Medicine (2013) (National Academy of Medicine, as of 2015), firearm suicides significantly outnumber firearm homicides for most age groups, accounting for approximately two-thirds of all firearm injury fatalities in the Un...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
Abstract The human immunodeficiency virus (HIV) epidemic among adolescent girls and young women (AGYW) in sub-Saharan Africa is a critical public health problem. We assessed whether depressive symptoms in AGYW were longitudinally associated with incident HIV, and identified potential social and behavioral mediators. Data came from a randomized trial of a cash transfer conditional on school attendance among AGYW (ages 13 - 21) in rural Mpumalanga Province, South Africa during 2011-2017. We estimated the relationship between depressive symptoms and cumulative HIV incidence using a linear probability model, and asses...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research
Nationwide, the opioid epidemic continues to have a significant and widespread adverse impact on morbidity and mortality. The number of individuals dying by suicide and unintentional overdose has continued to increase over the past decade, with opioids bei...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
PMID: 31651029 [PubMed - as supplied by publisher]
Source: Health and Social Work - Category: International Medicine & Public Health Authors: Tags: Health Soc Work Source Type: research
This study shows that although inflammation caused by SP infection alone was temporary, preceding IAV infection provided favorable conditions for SP colonization and multiplication by destroying lung structure and suppressing humoral immunity. Synergistic IAV-SP coinfection is likely to facilitate more SP colonization and promote B lymphocyte-suppression and reduction. Eventually, the pneumonia worsened. PMID: 31637902 [PubMed - in process]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
More News: Brain | Depression | Epidemics | Epidemiology | Health | Neurology | Respiratory Medicine