Riluzole as an Adjunctive Therapy to Risperidone for the Treatment of Irritability in Children with Autistic Disorder: A Double-Blind, Placebo-Controlled, Randomized Trial.

CONCLUSION: Riluzole add-on therapy shows several therapeutic outcomes, particularly for improving irritability, in children with autism. However, its add-on to risperidone also results in significantly increased appetite and weight gain. PMID: 23821414 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23821414?dopt=Abstract

Source: Paediatric Drugs - July 3, 2013 Category: Pediatrics Authors: Ghaleiha A, Mohammadi E, Mohammadi MR, Farokhnia M, Modabbernia A, Yekehtaz H, Ashrafi M, Hassanzadeh E, Akhondzadeh S Tags: Paediatr Drugs Source Type: research