Outbreak of Multidrug-resistant Pseudomonas Aeruginosa Endophthalmitis Due to Contaminated Trypan Blue Solution.
Conclusion: Positive microbiology and genomic DNA typing results proved that the contaminated trypan blue solutions were the source of infection in this outbreak. Postoperative endophthalmitis caused by Pseudomonas aeruginosa is often associated with a poor visual prognosis despite prompt treatment with intravitreal antibiotics. PMID: 31660104 [PubMed]
ConclusionThe emergence of MDR and toxigenic C. difficile suggesting hypervirulent strains in clinical settings is a concern. Resistance to vancomycin and metronidazole as last-line therapeutic resorts necessitate accomplishment of proper control strategies.
Biochemist and ophthalmologist whose research concentrated on the formation of cataractsRuth van Heyningen, who has died aged 101, was a pioneering explorer of ophthalmic biochemistry, a field to which she made major contributions after she joined the Nuffield Laboratory of Ophthalmology, at Oxford University, in 1951.Her research, much of which was carried out in collaboration with the laboratory ’s then director,Antoinette (Tony) Pirie, was focused on the lens, in particular the biochemical pathways involved in the formation of cataracts. Tony and Ruth wrote a key book together, Biochemistry of the Eye (1956), whic...
ConclusionA new SGI1 variant, SGI1-XJ9S, was characterized in this study for the first time. The draft genome sequence of S. Kentucky ST198 strain XJ9S isolated from poultry slaughter house provides valuable information for tracing the potential spread of this MDR clone from poultry products processing to consumption, even to humans.
Chikungunya (CHIK) fever is a tropical arbovirosis characterized by sudden fever, headache, rash, and severe arthralgia. The disease has been suggested to act as a trigger for several autoimmune disorders, especially rheumatoid arthritis. This abstract reports 2 cases of Sj ögren syndrome (SS) following CHIK infection. Both patients were female and presented with fever, arthralgia, rash, and arthritis during CHIK outbreak in Recife, Brazil. After several months, they developed severe sicca symptoms and 1 of them presented with parotid enlargement.
GIDEON what’s new summary: December 13 to December 15, 2019 Infectious Diseases – Outbreaks (45 updates) 45 DiseasesMap Infectious Diseases – Diseases (237 updates) 12 Clinical notes73 Diseases152 Country notesMap Infectious Diseases – Vaccines (1 updates) 1 Vaccine Microbiology – Bacteria (1 updates) 1 Bacteria The post Update: December 15, 2019 appeared first on GIDEON - Global Infectious Diseases and Epidemiology Online Network.
72 measles-related deaths have been recorded since the outbreak started.
A resurgence of measles cases has been seen in all WHO Regions since 2017. In the Asia Pacific Region, outbreaks of measles have been reported from countries where measles has previously been eliminated (including Australia, Cambodia, Japan, New Zealand, Republic of Korea) and in endemic countries with high incidence rates (including Lao PDR, Malaysia, the Philippines, Thailand and Viet Nam).
CONCLUSION: The present study provides detailed estimates for AACG incidence according to all age groups and gender through the 5-year study period. PMID: 31833263 [PubMed - in process]
In this study, the underlying mechanism of nitrite on the susceptibility of tilapia leucocytes to Streptococcus agalactiae (S. agalactiae) was studied. We found that a high dose of heat-killed S. agalactiae decreased tilapia leucocytes cell viability, whereas nitrite decreased the cell viability of leucocytes exposed to a low dose of bacteria. Bacterial challenge increased the production of nitric oxide (NO), whereas nitrite and bacteria coexposure caused higher NO production than nitrite or bacterial exposure alone. Cell viability increased after elimination of NO, and negative correlations existed between cell viability ...
CONCLUSIONS: Primary ocular toxoplasmosis presenting in adulthood is a relatively uncommon cause of posterior uveitis in New Zealand. This condition should be considered in any patient presenting with retinitis or optic nerve inflammation without a retinochoroidal scar. This disease tends to relapse; thus, close follow-up is required. PMID: 31833248 [PubMed - in process]