Alterations in serum levels of copper, zinc, and selenium among children with sickle cell anemia
This study investigates the serum levels of Cu, Zn, and Se among children with SCA. Materials and methods: This cross-sectional study was performed at King Khalid University Hospital, Riyadh. Thirty-three children with SCA in steady state and 33 age- and sex-matched normal healthy children were included in the study. Cu, Zn, and Se levels were measured by inductively coupled plasma-mass spectrometry (ICP-MS) instrument. Results: The median serum Cu levels among SCA patients (1.3 μg/mL) were higher than those of the controls (0.88 μg/mL; P
Condition: Sickle Cell Anemia in Children Interventions: Dietary Supplement: Acacia Senegal extract; Dietary Supplement: Pectin Sponsors: Al-Neelain University; University of Khartoum Recruiting
Adakveo and Oxbryta could be revolutionary treatments, but each costs about $100,000 per year and must be taken for life.
A 34 year-old female with Stage V chronic kidney disease secondary to a history of sickle cell anemia and focal segmental glomerulosclerosis and on peritoneal dialysis presented to our hospital for imaging as part of routine evaluation for renal transplant. Upon receiving an MRI of the abdomen to evaluate liver architecture and kidney anatomy, a 6.6 cm left perinephric mass was incidentally found inferomedial to the left kidney and extending caudally (Figure 1). The renal parenchyma and ureter were uninvolved.
Conditions: Cardiovascular Diseases; Sickle Cell Disease; Exercise Intervention: Other: Exercise Treatment Group Sponsor: University of Alabama at Birmingham Not yet recruiting
This study was carried out to compare the fetomaternal outcome in patients with SCD with those without SCD. This was a retrospective cohort study done in the Eastern Province of Saudi Arabia in a tertiary care, teaching hospital, by retrieving the data through the code ICD-9 for SCD, the control group was also selected with comparable characteristics. A total of 302 SCD pregnant patients were included for comparison with 600 pregnant women without SCD as control, during the period of Jan 1, 2008 to December 31, 2018. After the data retrieval, percentages of complications were calculated between the study and control groups...
Study Design: A retrospective study. Objective: To determine the impact of sickle cell anemia on perioperative outcomes and resource utilization in elective spinal fusion surgery. Summary of Background Data: Sickle cell anemia has been identified as an important surgical risk factor in otolaryngology, cardiothoracic surgery, general surgery, and total joint arthroplasty. However, the impact of sickle cell anemia on elective spine surgery is unknown. Methods: Hospitalizations for elective spinal fusion surgery between the years of 2001–2014 from the US National Inpatient Sample were identified using ICD-9-C...
Plastic bronchitis is a potentially fatal disorder characterized by the exudation of proteinaceous material and cells in the airways that leads to branching cast formation, which can be expectorated or lead to asphyxiation. Plastic bronchitis can appear as a complication after single-ventricle palliation. Other causes of plastic bronchitis that have been described include cystic fibrosis, sickle-cell anemia, asthma, and lymphangiomatosis. The underlying pathophysiology of plastic bronchitis seems to be abnormal pulmonary lymphatic perfusion, and the preferred treatment is embolization of the abnormal pulmonary lymphatic vessels (1).