Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion

ConclusionsNck adaptors in interaction with Dok1 induce podosome biogenesis and ECM degradation facilitating cancer cell invasion, and therefore a bona fide target of cancer therapy.

Source: Cancer Medicine - October 21, 2019 Category: Cancer & Oncology Authors: Sankar P. Chaki, Rola Barhoumi, Gonzalo M. Rivera Tags: ORIGINAL RESEARCH Source Type: research