Long-term endemic situation caused by a linezolid- and methicillin-resistant clone of Staphylococcus epidermidis in a tertiary hospital

ConclusionAn ST2 LZD- and methicillin-resistant clone was established in the whole hospital, not only in the ICU but also in wards where LZD consumption is low. This highlights the need to implement and maintain infection control measures as well as antimicrobial stewardship programs in all hospital units, to preserve the efficacy of LZD.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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CONCLUSIONS: Our results show that a predominant ST59 CA-MRSA has been introduced into the PICU to a significant extent. This has caused the ST59 HA-MRSA and CA-MRSA in the PICU to be indistinguishable. Our results also demonstrate that when we are interpreting situations where the causative agents of infections focus on very limited pathogenic clones, combined typing methods and epidemiological information are needed to investigate isolates' genetic and phenotypic diversity to distinguish an outbreak from endemic cases. PMID: 29458545 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Carrie Arnold is a freelance science writer living in Virginia. Her work has appeared in Scientific American, Discover, New Scientist, Smithsonian, and more. Background image: Reprinted by permission from Macmillan Publishers Ltd: doi:10.5923/s.microbiology.201401.02 About This Article open Citation: Arnold C. 2015. Outbreak breakthrough: using whole-genome sequencing to control hospital infection. Environ Health Perspect 123:A281–A286; http://dx.doi.org/10.1289/ehp.123-A281 Published: 1 November 2015 PDF Version (2.7 MB) The level of detail provided by whole-genome sequencing could give hospita...
Source: EHP Research - Category: Environmental Health Authors: Tags: Featured Focus News November 2015 Source Type: research
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