Case report: hearing loss after snorting oxymorphone

2.5 out of 5 stars Oxymorphone Insufflation Associated with Acute Sensorineural Hearing Loss: Case Files of the University of Massachusetts Medical Toxicology Fellowship. Boyle KL, Rosenbaum CD. J Med Toxicol 2013 Jun:9:179-183. No abstract available This case report describes a 37-year-old man who experienced transient partial hearing loss after snorting crushed Opana® (oxymorphone). The case itself isn’t much, but it provides the opportunity for the authors to present a good discussion of drug-induced ototoxicity. Although opiate-associated hearing loss (OAHL) is well described, the authors state that this is the first such case involving oxymorphone. OAHL has occurred after both acute and chronic use. In all cases that have been thoroughly evaluated, the hearing impairment is sensorineural, apparently from drug effect on the cochlea. It is often permanent but can be successfully treated with cochlear implantation. The authors note that other drug-related causes of hearing loss include: antibiotics (aminoglycosides, macrolides, vancomycin) anticonvulsants (valproic acid) non-steroidal antiflammatory drugs anti-hypertensives (enalapril) antimalarial (quinine) antineoplastics (cisplatin) heavy metals (cobalt, mercury) loop diuretics (furosemide) organic solvents )e.g., carbon disulfide, toluene) For a more complete list of ototoxic drugs, click here. Insufflation of oxymorphone has been associated with at least one fatality. Related posts: Methadone induces heari...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical narcotics opana opiates ototoxicity sensorineural hearing loss Source Type: news