Drastically progressive lung cavity lesion caused by Actinomyces odontolyticus in a patient undergoing chemoradiotherapy: A case report and literature review

Publication date: Available online 14 October 2019Source: Respiratory Medicine Case ReportsAuthor(s): Takeshi Matsumoto, Yusuke Kusakabe, Masamitsu Enomoto, Naoki Yamamoto, Kensaku Aihara, Shinpachi Yamaoka, Michiaki MishimaAbstractPulmonary actinomycosis reportedly forms 15% of all cases of actinomycosis, and pulmonary Actinomyces odontolyticus is particularly rare. A 60-year-old man with a hoarse voice was referred to our hospital. Lung squamous cell carcinoma was diagnosed at the clinical tumor-node-metastasis stage of cT2N2M0, and concurrent chemoradiotherapy was initiated. Further, a small cavity was also detected in the left upper lobe, but it was observed. During chemoradiotherapy, the small cavity lesion rapidly increased accompanying infiltration, and administration of short-term antibiotics did not improve the patient's condition. Bronchoscopy did not show any diagnostic results. Although a rapidly progressive malignant lesion could not be excluded and surgical management was considered, resection could not be performed because of the tight adhesion of the mass. Therefore, bronchoscopy was performed again, and the bronchial lavage culture showed a positive smear for the Actinomyces species. Further, using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), the bacteria was identified as A. odontolyticus. After long-term administration of amoxicillin, the lung cavity with infiltration gradually improved. To the best of our kno...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research

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Publication date: Available online 16 November 2019Source: European Journal of Surgical OncologyAuthor(s): D. Moreno-Ramírez, R. Vieira, R. Kaufmann
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ara Y Abstract The impact of electrolytes on the adsorption of emerging pollutants: pharmaceuticals onto layered materials: a raw clay mineral and its nonionic and cationic organoclay derivatives was studied. The selected pharmaceuticals: amoxicillin, norfloxacin, sulfamethoxazole, metoprolol, carbamazepine, and trimethoprim show different electric charges: zwitterionic, anionic, cationic and neutral and hydrophobic character (different LogP). Without any salts, the set of complementary data obtained by UV and infrared spectroscopies, X-ray diffraction points out the importance of the electric charge which represe...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Publication date: Available online 15 November 2019Source: The Journal of Chemical ThermodynamicsAuthor(s): Wanxin Li, Ali Farajtabar, Rong Xing, Yiting Zhu, Hongkun ZhaoAbstractThe mole fraction solubility of amoxicillin in four co-solvent mixtures of N,N-dimethylformamide (DMF) + water (2), isopropanol (1) + water (2), N-methyl pyrrolidone (NMP) (1) + water (2) and ethylene glycol (EG, 1) + water (2) at temperatures from 278.15 K to 328.15 K was determined by means of the shake-flask technique. At the same temperature and composition of DMF, isopropanol, NMP or EG, the solubility magnitude of amoxicillin was highest in t...
Source: The Journal of Chemical Thermodynamics - Category: Chemistry Source Type: research
Authors: Park SH, Lim JH, Jeong J, Lee SH, Cha HJ, Choi Y, Jo JC PMID: 31730691 [PubMed]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research
Authors: Dib J Abstract I read with great interest the paper by Sousa M. Tumor seeding of the fistula tract should be suspected in patients with a previous history of esophageal or nasopharynx squamous cell carcinoma who have undergone a Percutaneous Endoscopic Gastrostomy (PEG) with a persistent gastrocutaneous fistula. Especially after the use of an OTSC. In fact, the "pull technique" for PEG tube placement should not be used in this context. PMID: 31729232 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
We examined US sensitivity for diagnosis of HCC in obese patients. Methods: Liver transplant patients data with HCC in explant was used (January 2012-December 2017). All patients underwent liver US within 3 months of diagnosis of HCC. Number/size of HCC lesions were extracted from radiologic and pathologic reports. Obesity was defined as BMI ≥30 kg/m2. Results: One hundred sixteen patients were included. 80% were male, with mean BMI of 31 kg/m2. The most common underlying liver disease was hepatitis C virus (62%). At the time of diagnosis, median number of HCC lesions was 2 (interquartile range [IQR], 1-3), and ...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Publication date: Available online 15 November 2019Source: Diagnostic and Interventional ImagingAuthor(s): S. Young, M. Rivard, R. Kimyon, T. SanghviAbstractPurposeTo compare manufacturer provided predictions and realized ablation dimensions in the liver using one 2450 MHz 100 Watt generator model microwave ablation (MWA) system.Materials and methodBetween 1/1/2015 and 2/1/2018, MWAs were performed in 86 patients who underwent a total of 103 MWAs with a single MWA system. There were 64 men and 22 women with a mean age of 63.9 ± 9.9 (SD) years (range: 30–88 years). Demographic, procedural, and ou...
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Publication date: Available online 15 November 2019Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Fábio Muradás Girardi, Vivian P. Wagner, Manoela Domingues Martins, Aliende Lengler Abentroth, Luiz Alberto HauthAbstractIntroductionRegional metastases of cutaneous head and neck squamous cell carcinoma occur in approximately 5 % of cases, being the most important prognostic factor in survival, currently with no distinction between parotid and neck metastasis.ObjectiveThe purpose of this study was to evaluate the prognostic features among patients with head and neck cutaneous squamous cell carcinoma ...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
CONCLUSIONS Bioinformatics analysis, combined with patient survival analysis, identified PTK7 gene expression as a potential therapeutic target and prognostic biomarker for all stages of HCC. PMID: 31730575 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Abstract BACKGROUND: Treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) with programmed cell death protein 1 (PD-1) inhibitors has been associated with risk of developing immune-mediated adverse reactions (IMARs). OBJECTIVES: This review provides nurses with an overview of the safety of PD-1 inhibitors approved by the U.S. Food and Drug Administration for recurrent or metastatic SCCHN following platinum chemotherapy, as well as recommendations for assisting with the diagnosis and management of IMARs. METHODS: PubMed® searches were conducted to iden...
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
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