Spontaneous regression of primary endobronchial extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
Publication date: Available online 20 March 2019Source: Respiratory Medicine Case ReportsAuthor(s): Chiaki Hosoda, Takashi Ishiguro, Nobumasa Takahashi, Nobufumi Kamiishi, Yoshihiko Shimizu, Noboru TakayanagiAbstractExtranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) of pulmonary origin is a relatively rare disease. In particular, reports of MALT lymphoma occurring and localized in the trachea or bronchus have been limited. Pulmonary MALT lymphoma has been reported to demonstrate spontaneous regression, whereas there is only one reported case of spontaneous regression of primary endobronc...
Source: Respiratory Medicine Case Reports - March 22, 2019 Category: Respiratory Medicine Source Type: research

Acute eosinophilic pneumonia following electronic cigarette use
We present the first case of AEP involving a young female after use of e-cigarettes. Clinicians should consider AEP when evaluating young patients with hypoxic respiratory failure and a recent history of e-cigarette use. This case highlights the need for more research into the relationship between e-cigarettes and AEP. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - March 19, 2019 Category: Respiratory Medicine Source Type: research

Pressure Regulated Volume Control (PRVC): Set it and forget it?
We describe two cases where this adaptive mode of ventilation became maladaptive leading to patient-ventilator dyssynchrony. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - March 9, 2019 Category: Respiratory Medicine Source Type: research

Bilateral diffuse pulmonary infiltrates secondary to malignant peritoneal mesothelioma – A rare clinical presentation
In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse pulmonary opacities in association with primary malignant peritoneal mesothelioma. The diagnosis was confirmed by ultrasound guided abdominal and bronchoscopy, trans-bronchial lung biopsy. The biopsy demonstrated positive staining with AE1/3, CK7, CK5/6, WT1, calretinin and D2 40. The cells were negative for BerEP4, PAX8, CA125, ER, CD34, ERG, P63, P40, Melan A, Gata3 and mammaglobin. The morphology and immunohistochemical profile supported a diagnosis of epithelioid malignant mesothelioma. (S...
Source: Respiratory Medicine Case Reports - March 5, 2019 Category: Respiratory Medicine Source Type: research

A case report of reversible bronchiectasis in an adult: Pseudobronchiectasis
We report a case of reversible bronchial dilatation in an adult as evidenced by high-resolution computed tomography, which demonstrates that, although quite rare in adults, spontaneous resolution may occur. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - March 5, 2019 Category: Respiratory Medicine Source Type: research

Mycobacterium goodii pneumonia: An unusual presentation of nontuberculous mycobacterial infection requiring a novel multidisciplinary approach to management
ConclusionsThis is an unusual case of organizing pneumonia related to Mycobacterium goodii infection and highlights the importance of mycobacterial culture in unusual and unresolving cases of organizing pneumonia. The importance of controlling symptoms related to gastric dysmotility and aspiration is also addressed. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - March 1, 2019 Category: Respiratory Medicine Source Type: research

Therapeutic effect of nintedanib on acute exacerbation of interstitial lung diseases
Publication date: Available online 28 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Yoko Ito, Gen Tazaki, Yusuke Kondo, Genki Takahashi, Fumio SakamakiAbstractAlthough the development of new antifibrotic agents (pirfenidone, nintedanib) has modified the disease progression of idiopathic pulmonary fibrosis (IPF), there is still no effective treatment for acute exacerbation of interstitial lung diseases (ILD) including IPF. We herein report a case of acute exacerbation of ILD (AE-ILD) treated only with nintedanib without any environmental changes and any other medications such as corticosteroid therapy, di...
Source: Respiratory Medicine Case Reports - February 28, 2019 Category: Respiratory Medicine Source Type: research

Disseminated tuberculosis with severe immune thrombocytopenia
We present an uncommon and interesting case of severe isolated immune thrombocytopenia secondary to bilateral tubercular cervical lymphadenopathy and pott's spine in 26 year old Indian male. Due to severe thrombocytopenia patient was managed with IVIg and steroids along with anti tubercular therapy. Early diagnosis and treatment with Anti tubercular therapy is important for effective control of bleeding manifestations. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 26, 2019 Category: Respiratory Medicine Source Type: research

Spontaneous idiopathic pulmonary vein thrombosis successfully treated with Warfarin: A case report and review of the literature
We present a 68-year-old woman who was undergoing treatment for recurrent urinary tract infection (UTI) but was incidentally noted to be dyspneic and intermittently hypoxic. She was found to have idiopathic pulmonary vein thrombosis that was successfully managed with systemic anticoagulation. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 23, 2019 Category: Respiratory Medicine Source Type: research

Mycoplasma pneumonia with hydropneumothorax: A case report
Publication date: Available online 22 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ateeq Mubarik, Aamani Jupalli, Arshad Muhammad Iqbal, Sohaib Khaleel Mohammed, Salman Muddassir, Eddib AbdulmagidAbstractMycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in adults. Mycoplasma pneumoniae pneumonia (MPP) presents with pulmonary and extrapulmonary manifestations. Pneumothorax is a rare MPP complication in children. But, we reported a case of MPP with hydropneumothorax in an adult. The association of MPP, hydropneumothorax, and empyema is extremely rare. (Source: Respirat...
Source: Respiratory Medicine Case Reports - February 23, 2019 Category: Respiratory Medicine Source Type: research

Recurrent intrathoracic dedifferentiated liposarcoma: A case report and literature review
ConclusionIntrathoracic LPS is a rare tumor. Recurrence is higher with dedifferentiated histology forms. Radical surgery with excision of margins is the primary recommended treatment. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 22, 2019 Category: Respiratory Medicine Source Type: research

Acute hypoxic respiratory failure secondary to antisynthetase syndrome: A case report and review of literature
ConclusionThis supports the fact that antisynthetase syndrome most commonly presents with lung and muscle manifestations simultaneously. The fact that our case presented with lung findings alone led to the delay in his diagnosis. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 22, 2019 Category: Respiratory Medicine Source Type: research

A 75 year old male with recurrent unilateral pleural effusion and positive ANA
Publication date: Available online 22 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Tanner Wallen, Nikhil Jagan, Mridula Krishnan, Zachary DepewAbstractThis case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classic...
Source: Respiratory Medicine Case Reports - February 22, 2019 Category: Respiratory Medicine Source Type: research

Efficacy of immunotherapy in sarcomatoid lung cancer, a case report and literature review
In this report, based on a case of stage IV lung sarcomatoid carcinoma with an extraordinary evolution and survival over 4 years, we address unresolved questions about the treatment of this cancer. We also make a literature review about the key factors that characterize this histology and that should be considered when treating those patients. Sarcomatoid carcinoma presents with mutations as KRAS, EGFR, ALK or MET in up to 70% of cases, and an important expression of PD-L1 (also called B7-H1), which can influence treatment of those patients with new drugs as immune checkpoint inhibitors. Immunotherapy has changed the horiz...
Source: Respiratory Medicine Case Reports - February 21, 2019 Category: Respiratory Medicine Source Type: research

Rapid effects of benralizumab on severe asthma during surgery for residual tumor after advanced lung adenocarcinoma treatment with pembrolizumab
Publication date: Available online 19 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Takehiro Izumo, Yuriko Terada, Mari Tone, Minoru Inomata, Naoyuki Kuse, Nobuyasu Awano, Atsuko Moriya, Tatsunori Jo, Hanako Yoshimura, Yoshiaki FuruhataAbstractSevere bronchial asthma is a chronic disorder of the airways that may be accompanied by comorbid diseases. Invasive treatment, including surgery, in patients with severe asthma has limitations depending on the degree of control of the asthma. A 71-year-old woman was diagnosed with adenocarcinoma with high programmed death-ligand 1 (PD-L1) expression and cT3N0M1a. A...
Source: Respiratory Medicine Case Reports - February 20, 2019 Category: Respiratory Medicine Source Type: research

The use of lobectomy for management of clinically significant pulmonary vein stenosis and occlusion refractory to percutaneous intervention
We present a case of iatrogenic PVO and ipsilateral severe PVS post RFA who underwent attempted lobectomy for persistent exertional dyspnea and persistent hypoperfusion of the left upper lung lobe despite percutaneous intervention and six months of optimal medical therapy. The lobectomy was aborted due to the presence of a significant fibrothorax, and the patient continues to have significant exercise limitation despite participation in pulmonary rehabilitation. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 17, 2019 Category: Respiratory Medicine Source Type: research

An application of pacemaker respiratory monitoring system for the prediction of heart failure
Publication date: Available online 16 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Takashi Koyama, Masanori Kobayashi, Tomohide Ichikawa, Tadamasa Wakabayashi, Hidetoshi AbeAbstractSleep-disordered breathing (SDB) is one of the most common complications among heart failure (HF) patients. Changes of respiratory patterns during the various stages in patients with HF have not been fully investigated. In this case, the algorism using thoracic impedance sensor and minute ventilation (sleep apnea monitoring [SAM] algorithm) with implanted pacemaker (REPLY 200 SR or DR, Sorin CRM SAS, Clamart, France) was used...
Source: Respiratory Medicine Case Reports - February 17, 2019 Category: Respiratory Medicine Source Type: research

ITGB (Integrin subunit beta) 3 mutation involved in pulmonary hemorrhage and osteopetrosis
We report on a previously healthy infant who presented with pulmonary hemorrhage due to a rare hematologic disorder. He also had imaging and laboratory studies suggestive of osteopetrosis. A genetic testing uncovered a previously known integrin gene possibly involving both hematologic and bone tissues; however, the latter has been described only in mouse models. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 17, 2019 Category: Respiratory Medicine Source Type: research

Respiratory dysfunction following initiation of mirabegron: A case report
Conclusions: The mechanism of this adverse effect is unknown, but we speculate that this effect may be potentially mediated by the effect of β3 adrenergic receptor agonism on skeletal muscle, in this case in a patient with pre-existing neuromuscular disease. Careful assessment of patients who develop shortness of breath while on mirabegron should include an assessment for restrictive lung disease secondary neuromuscular dysfunction. Additional study is needed of the effects of β3 agonism on skeletal muscle. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 17, 2019 Category: Respiratory Medicine Source Type: research

Multifocal pulmonary mucinous cystic neoplasm with ovarian-like stroma: Once in a blue moon-case report
Publication date: Available online 16 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Sarah Shawash, Riad Abdeljalil, Hussam HaddadAbstractMucinous cystic neoplasm of the lung is a rare well known entity in the WHO classification of lung tumors. It is defined as “a localized cystic mass filled with mucin and surrounded by a fibrous wall lined by well-differentiated columnar mucinous epithelium.” The presence of ovarian-like stroma is not mentioned in this definition. Reviewing the literature, we have found only one reported case mentioning this finding, described by Geramizadeh et al., in 2014....
Source: Respiratory Medicine Case Reports - February 17, 2019 Category: Respiratory Medicine Source Type: research

Pulmonary sclerosing pneumocytoma, a rare tumor of the lung
We presented a case of PSP in a 50-year-old woman who was diagnosed with a nodular lesion in the right lung. Thoracotomy was used for the excision of the mass. Pathologic examination revealed no malignant cells. Immunohistochemical studies were performed. TTF-1 was (+), Napsin-A was found to be weakly (+). After surgical resection, the patient was followed up. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 14, 2019 Category: Respiratory Medicine Source Type: research

Chinese herbal medicine Qing-Dai-induced pulmonary arterial hypertension in a patient with ulcerative colitis: A case report and experimental investigation
We present the case of a man with ulcerative colitis who was diagnosed with idiopathic PAH. After initiating oral beraprost therapy, the patient showed significant hemodynamic improvements and an unusual course of clinical recovery. In 2016, the Japanese Ministry of Health, Labour, and Welfare issued a warning regarding the possible side effects of Qing-Dai. We learned that our patient had been taking self-purchased Qing-Dai for 2 years. Therefore, we performed an experimental study and determined that Qing-Dai may cause PAH through a mechanism involving nitric oxide synthase inhibition and pulmonary artery endothelial dys...
Source: Respiratory Medicine Case Reports - February 9, 2019 Category: Respiratory Medicine Source Type: research

Rare case of primary extranodal marginal zone lymphoma of the thorax
We report a case of a 64-year-old man with no history of HIV infection or pyothorax who presented with dry cough, right pleuritic pain and dyspnea. A computed tomography scan revealed an irregular pleural mass invading his right chest wall with pleural effusion. CT-guided needle biopsy revealed extranodal marginal zone B-cell lymphoma. The patient was treated with chemotherapy and radiotherapy. The patient has 9 years of follow up with 2 relapse's episodes. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 8, 2019 Category: Respiratory Medicine Source Type: research

Combination of pleuroparenchymal fibroelastosis with non-specific interstitial pneumonia and bronchiolitis obliterans as a complication of hematopoietic stem cell transplantation — Clues to a potential mechanism
We report a case of 30-year-old man who developed a unique combination of pleuroparenchymal fibroelastosis with cellular and fibrotic non-specific interstitial pneumonia (NSIP) and bronchiolitis obliterans (BO) sixteen years after hematopoietic stem cell transplantation. Histological examination revealed almost exclusive infiltration of CD3-positive T lymphocytes associated with lymphoepithelial lesions and multi-focal denudation of covering epithelial cells in all components. This case suggests PPFE, NSIP, and BO might be conditions of the same spectrum, pathogenetically related to chronic graft-versus-host disease. Immun...
Source: Respiratory Medicine Case Reports - February 5, 2019 Category: Respiratory Medicine Source Type: research

Massive hemoptysis due to recurrence of bronchial to pulmonary vascular malformation: A case report
We present a case of a 69-year-old male with a recurrent episode of hemoptysis three years after treatment for a bronchial dieulafoy lesion. The bronchoscopy done three years prior during an initial episode of hemoptysis showed a visible dieulafoy deep within a subsegmental branch of the right lower lobe. This case is unique because there are no other reports within the literature of a delayed recurrence several years after previous treatment of a bronchial dieulafoy lesion, which in our case was due to bronchial to pulmonary vascular malformation. Bronchial arteriography revealed a bronchial artery to pulmonary artery vas...
Source: Respiratory Medicine Case Reports - February 5, 2019 Category: Respiratory Medicine Source Type: research

Bullet in tracheobronchial tree without lung contusion removed by fibreoptic bronchoscopy in two parts
Publication date: Available online 5 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ashish K. Prakash, Anand Jaiswal, Ankit Aggarwal, B. Datta, Sangeeta Khanna, K.K. Handa, Yatin MehtaAbstractA person presented with multiple gunshot injury. Chest x-ray & CT whole body trauma protocol was done which showed multiples pellets of bullet in abdomen and one bullet in elbow according to entry wound. There was an entry wound without any bullet in left maxillofacial region however there was no exit wound. A bullet was noticed in tracheobronchial tree. There was no pneumothorax any signs of chest trauma or any ...
Source: Respiratory Medicine Case Reports - February 5, 2019 Category: Respiratory Medicine Source Type: research

Chylothorax after spinal fusion surgery: A case report and literature review
Publication date: Available online 5 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Kazutoshi Toriyama, Nariaki Kokuho, Chika Yajima, Junichiro Kawagoe, Yuuki Togashi, Takao Tsuji, Hideaki Nakayama, Shinji AbeAbstractChylothorax is reported as a postoperative complication, mainly in the field of thoracic surgery, but there are only 14 reports in the field of spinal surgery.A 64-year-old woman underwent spinal fusion surgery by the anterior and posterior approach for her scoliosis. She developed leg edema and right pleural effusion 2 months after the surgery. Laboratory findings showed decreased total prot...
Source: Respiratory Medicine Case Reports - February 5, 2019 Category: Respiratory Medicine Source Type: research

A case of nivolumab-induced isolated adrenocorticotropic hormone (ACTH) deficiency
Publication date: Available online 28 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Yozo Sato, Yosuke Tanaka, Mitsunori Hiron, Masahiro Seike, Akihiko GemmaAbstractOne of the novel PD-1 antibodies/immune checkpoint inhibitors, nivolumab is reported to be associated with a wide range of immune-related adverse events (irAEs). We hereby report a case of isolated adrenocorticotropic hormone (ACTH) deficiency developing in a patient with squamous cell lung cancer (SCC) during nivolumab therapy.CaseA 79-year-old man with SCC was started on nivolumab therapy as a fifth-line treatment after 4 lines of cytotoxic a...
Source: Respiratory Medicine Case Reports - January 29, 2019 Category: Respiratory Medicine Source Type: research

Bilateral pneumothorax after pacemaker placement “Buffalo chest”
We describe an 83-year-old female without prior history of cardiothoracic surgery, trauma or lung disease, who underwent dual chamber pacemaker placement using a left subclavian vein access and developed bilateral pneumothoraces following the procedure. The bilateral pneumothoraces were completely resolved with single left-sided thoracostomy tube placement suggesting the patient had “Buffalo chest”. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 29, 2019 Category: Respiratory Medicine Source Type: research

Interstitial pneumonia induced by cyclophosphamide: A case report and review of the literature
ConclusionAlthough interstitial lung disease induced by CP is rare, with the current widespread usage of CP increases the risks of diffuse interstitial pneumonia and pulmonary fibrosis, which need to be noted in time to get early treatment. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 27, 2019 Category: Respiratory Medicine Source Type: research

Case of both rivaroxaban- and dabigatran-induced leukocytoclastic vasculitis, during management of pulmonary thromboembolism
Publication date: Available online 25 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Hong Lyeol Lee, Lucia Kim, Cheol Woo Kim, Jung Soo Kim, Hae Sung Nam, Jeong Seon RyuAbstractLeukocytoclastic vasculitis is a disorder characterized by neutrophilic inflammation that is predominantly limited to the superficial cutaneous postcapillary venules. This condition may be idiopathic or may have a defined cause. Rivaroxaban and dabigatran have been widely used as warfarin alternatives, because of their efficacy and safety. In this case report, we describe a case of leukocytoclastic vasculitis induced by both rivarox...
Source: Respiratory Medicine Case Reports - January 25, 2019 Category: Respiratory Medicine Source Type: research

Cavitary tuberculosis re-emerging in immigrant children
ConclusionSevere forms of tuberculosis may re-emerge and BCG vaccination should remain part of the immunization programme in immigrant populations. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 23, 2019 Category: Respiratory Medicine Source Type: research

An unusual variant of scimitar syndrome predisposing to recurrent pneumonia
We present an unusual case of scimitar syndrome with associated recurrent pneumonia. We will briefly review the literature on scimitar syndrome as well as discuss how a predisposition to recurrent pneumonia may develop in this unusual variant of a rare clinical entity. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 23, 2019 Category: Respiratory Medicine Source Type: research

Miliary tuberculosis presenting as bilateral superficial femoral artery mycotic aneurysm in an immunocompetent patient
Publication date: Available online 23 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Fatehi Elzein, Nabeel Qatan, Abdullah Alghamdi, Ali Albarrak, Kiran KalamAbstractMycotic tuberculous aneurysm is extremely rare. The aorta is the main affected artery however; iliac and less commonly femoral arteries can also be affected. In 75% of the cases a contagious focus leads to infection through erosion of the vessel wall; on the other hand direct seeding of the blood vessel wall via the vasa vasorum may occur in 25%. In a large number of patients it may be a manifestation of miliary tuberculosis. In this case repo...
Source: Respiratory Medicine Case Reports - January 23, 2019 Category: Respiratory Medicine Source Type: research

A different clinical presentation of Heiner syndrome: The case of diffuse alveolar hemorrhage causing massive hemoptysis and hematemesis
Publication date: Available online 23 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ayse Selcan Koc, Asena Sucu, Umit CelikAbstractHeiner syndrome is a non-IgE-mediated hypersensitivity to cow's milk, which often causes pulmonary disease in infants and young children. Patients often have symptoms of chronic or recurrent upper or lower respiratory tract infection. It has been reported that the Heiner’s syndrome can cause recurrent pulmonary hemorrhage, and it is difficult to differentiate from the entity of idiopathic pulmonary hemosiderosis, another disease with recurrent pulmonary hemorrhage of unk...
Source: Respiratory Medicine Case Reports - January 23, 2019 Category: Respiratory Medicine Source Type: research

Chest wall lipoblastoma in a 3 year-old boy
ConclusionAlthough extremely rare, chest wall lipoblastoma should be included in the differential diagnosis of thoracic mass in childhood. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 20, 2019 Category: Respiratory Medicine Source Type: research

Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior
Publication date: Available online 17 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Hee-Young Yoon, Hyun-Hae Cho, Yon Ju RyuAbstractMost adenovirus infections are self-limiting in immunocompetent individuals. Here, we report a case of adenovirus pneumonia in a 17-year-old immunocompetent male. He was admitted to our emergency room complaining of a febrile sense, cough, and diarrhea for four days. Crackles in the left lung and a high fever (40.7 °C) were revealed. Initial chest X-ray and computed tomography images showed consolidation in the left lung. We immediately started empirical antibiotic trea...
Source: Respiratory Medicine Case Reports - January 18, 2019 Category: Respiratory Medicine Source Type: research

Post-infective bronchiectasis by measles prior infection – A case report
Publication date: Available online 18 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Maria Braz, Ana Cristina Ferreira, Ana Sofia Sousa, Fernando BarataAbstractBronchiectasis (BE) refers to an abnormal and irreversible dilatation of the bronchi. Post-infectious etiology still remains an important and frequent cause. Associated the anti-vaccine movement, measles resurfaces and with all the outcomes that comes from the disease. The present case illustrates one of the possible complication of measles - BE, underlining the importance of vaccination. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 18, 2019 Category: Respiratory Medicine Source Type: research

Sudden cardiac death due to primary malignant pericardial mesothelioma: Brief report and literature review
Publication date: Available online 14 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Rafael Martínez-Girón, Liron Pantanowitz, Santiago Martínez-Torre, Joshua PantanowitzAbstractSudden cardiac death is an unexpected clinical condition that typically occurs due to a cardiac cause, generally within one hour of symptom onset, in people with known or unknown cardiac disease. Primary malignant pericardial mesothelioma, as a cause of sudden death, is an uncommon consequence of a rare disease. Herein, we present a case of cardiac tamponade due to a primary pericardial mesothelioma. Cytologica...
Source: Respiratory Medicine Case Reports - January 15, 2019 Category: Respiratory Medicine Source Type: research

Anti-MDA5 antibody-positive rapidly progressive interstitial pneumonia without cutaneous manifestations
Publication date: Available online 14 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Junichi Aoyama, Hiroki Hayashi, Chika Yajima, Hiroyuki Takoi, Toru Tanaka, Takeru Kashiwada, Nariaki Kokuho, Yasuhiro Terasaki, Ayumi Nishikawa, Takahisa Gono, Masataka Kuwana, Yoshinobu Saito, Shinji Abe, Masahiro Seike, Akihiko GemmaAbstractA 47-year-old man was referred to our hospital with a 1-month history of fever and dyspnea after inhalation of insecticide in a confined space. We diagnosed rapidly progressive interstitial pneumonia. High-dose methylprednisolone, tacrolimus, and intermittent infusion of cyclophospham...
Source: Respiratory Medicine Case Reports - January 15, 2019 Category: Respiratory Medicine Source Type: research

Spontaneous resolution of thoracic radiation therapy-induced organizing pneumonia: A case series
Publication date: Available online 10 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Hidenori Kawakami, Takao Miyabayashi, Chikako Tsubata, Kyuma Ota, Takashi Ishida, Osamu KobayashiAbstractWe retrospectively analyzed the data of 9 patients with organizing pneumonia induced by radiation therapy. Radiation therapy had been administered for breast cancer in 8 patients and for lung cancer in 1 patient. Symptoms were detected in 8 patients; however, none of the patients developed hypoxemia or respiratory failure, and the clinical course was good. Steroid therapy was administered to 3 patients; however, all 3 p...
Source: Respiratory Medicine Case Reports - January 11, 2019 Category: Respiratory Medicine Source Type: research

A pyo-hydropneumothorax with sepsis, secondary to Gardnerella vaginalis infection in a post-partum female
Publication date: Available online 10 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Lorraine Murray, James Halpin, Brian Casserly, Nuala H. O'Connell, Timothy ScanlonAbstractA 20 year old female, 14 days post partum, presented to the Emergency Department in severe respiratory distress. Imaging of her chest revealed a left tension hydropneumothorax with significant mediastinal displacement. A chest drain was inserted and over 4L of cloudy-brown malodourous fluid was drained. Gardnerella Vaginalis was isolated on culture of the fluid. The pyohydropneumothorax and associated sepsis, was refractory to managem...
Source: Respiratory Medicine Case Reports - January 11, 2019 Category: Respiratory Medicine Source Type: research

Pulmonary mucormycosis associated with medical marijuana use
Publication date: Available online 9 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Taylor Stone, Joseph Henkle, Vidhya PrakashAbstractA 66-year-old man with diabetes presented to the hospital with a two-month history of dyspnea, cough, rust-colored sputum, night sweats and 20 pound weight loss. He had begun smoking medical marijuana 3 months earlier. CT of the chest showed multiple bilateral large ground glass opacities with surrounding consolidation. Infectious workup was negative. BAL was non-diagnostic. He was treated with broad spectrum antibiotics without improvement. VATS was performed and cultured ...
Source: Respiratory Medicine Case Reports - January 10, 2019 Category: Respiratory Medicine Source Type: research

Bilateral spontaneous pneumothoraces in anaplastic thyroid cancer
We describe a 73 year old man who presented with recurrent tumor in the right neck, mediastinal lymphadenopathy and bilateral pulmonary nodules after thyroidectomy. He was treated with lenvatinib and presented with bilateral pneumothoraces. Anaplastic thyroid cancer is an aggressive subtype of thyroid cancer that has limited response to cytotoxic chemotherapy and poor prognosis. Recent reports show that targeted therapy with a multiple receptor tyrosine kinase inhibitor, lenvatinib, may have improvement in progression-free survival, but rarely pneumothorax has been reported in those with lung metastases. Various mechanisms...
Source: Respiratory Medicine Case Reports - January 8, 2019 Category: Respiratory Medicine Source Type: research

Clinical characteristics and treatments for bronchial Dieulafoy's disease
ConclusionAngiography can be used for diagnosis of Dieulafoy's disease of the bronchus, whereas bronchoscopy biopsy should be avoided. Interventions such as embolization or bronchial coagulation play an important role in patients with coughing with massive hemoptysis. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 7, 2019 Category: Respiratory Medicine Source Type: research

Lung injury from inhaling butane hash oil mimics pneumonia
We describe a lung injury as a result of BHO use.CaseA previously healthy 18-year-old female presented to the ED with shortness of breath for 3–4 days. Initial oxygen saturation was 79% on room air. She was refractory to bronchodilators, steroids and supplemental O2. She has a 1-pack year smoking history and daily BHO abuse. Chest x-ray was positive for bilateral patchy infiltrates with mild hyperinflation. CT was negative for Pulmonary Embolus or other acute pathologic process. Sputum gram stain and blood cultures were negative. Arterial blood gases confirmed a pO2 of 73 mmHg. On physical exam she was tachycardic ...
Source: Respiratory Medicine Case Reports - January 5, 2019 Category: Respiratory Medicine Source Type: research

Pembrolizumab-induced pneumonitis with a perilymphatic nodular pattern in a lung cancer patient: A radio-pathologic correlation
This report, in conjunction with existing literature, illustrates the wide variety of the pembrolizumab-induced pneumonitis and bolsters the current understanding of its pathophysiology. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 5, 2019 Category: Respiratory Medicine Source Type: research

Successful treatment of late onset empyema after extrapleural pneumonectomy: A case report
Publication date: Available online 4 January 2019Source: Respiratory Medicine Case ReportsAuthor(s): Shigeto Nishikawa, Shigeyuki Tamari, Kenji Okita, Koji ChiharaAbstractTreatment of post-extrapleural pneumonectomy empyema (PEPPE) is more difficult than that for post-pneumonectomy empyema for two reasons: first, a large infectious dead space remains after extrapleural pneumonectomy (EPP); and second, defects of the pericardium and diaphragm are reconstructed with artificial materials, which ideally should be removed for treatment of infection. Here, we report the case of a 56-year-old male with PEPPE that occurred long af...
Source: Respiratory Medicine Case Reports - January 5, 2019 Category: Respiratory Medicine Source Type: research

ARDS from miliary tuberculosis successfully treated with ECMO
We report the case of an 18 year old man where prolonged therapy (50 days) with extracorporeal membrane oxygenation (ECMO) allowed extensive lung damage from miliary tuberculosis to heal. The case reflects how challenging the diagnosis of tuberculosis may be and how difficult it is to reach adequate blood levels of anti-tuberculosis drugs while on ECMO. It's also an example of how indications for ECMO have been expanding the last years and that long term ECMO therapy is possible without serious complications. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - January 5, 2019 Category: Respiratory Medicine Source Type: research

Paraneoplastic limbic encephalitis revealing a small cell carcinoma of the lung
Conclusionswe insist on the diversity of the imaging findings, immunological analyses and outcome on treatment of this entity. Prognostic impact remains also unclear. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - December 27, 2018 Category: Respiratory Medicine Source Type: research