Transcriptional activation of CBF β by CDK11p110 is necessary to promote osteosarcoma cell proliferation

Aberrant expression of cyclin-dependent protein kinases (CDK) is a hallmark of cancer. CDK11 plays a crucial role in cancer cell growth and proliferation. However, the molecular mechanisms of CDK11 and CDK11 t...

Source: Cell Communication and Signaling - October 14, 2019 Category: Molecular Biology Authors: Yong Feng, Yunfei Liao, Jianming Zhang, Jacson Shen, Zengwu Shao, Francis Hornicek and Zhenfeng Duan Tags: Research Source Type: research