Vital Signs: Burden and Prevention of Influenza and Pertussis Among Pregnant Women and Infants - United States.
Vital Signs: Burden and Prevention of Influenza and Pertussis Among Pregnant Women and Infants - United States. MMWR Morb Mortal Wkly Rep. 2019 Oct 11;68(40):885-892 Authors: Lindley MC, Kahn KE, Bardenheier BH, D'Angelo DV, Dawood FS, Fink RV, Havers F, Skoff TH Abstract INTRODUCTION: Vaccinating pregnant women with influenza vaccine and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) can reduce influenza and pertussis risk for themselves and their infants. METHODS: Surveillance data were analyzed to ascertain influenza-associated hospitalization among pregnant women and infant hospitalization and death associated with influenza and pertussis. An Internet panel survey was conducted during March 27-April 8, 2019, among women aged 18-49 years who reported being pregnant any time since August 1, 2018. Influenza vaccination before or during pregnancy was assessed among respondents with known influenza vaccination status who were pregnant any time during October 2018-January 2019 (2,097). Tdap receipt during pregnancy was assessed among respondents with known Tdap status who reported a live birth by their survey date (817). RESULTS: From 2010-11 to 2017-18, pregnant women accounted for 24%-34% of influenza-associated hospitalizations per season among females aged 15-44 years. From 2010 to 2017, a total of 3,928 pertussis-related hospitalizations were reported among infants aged
To assess the safety and immunogenicity of simultaneous versus sequential tetanus, diphtheria, acellular pertussis vaccine (Tdap) and quadrivalent inactivated influenza vaccine (IIV4) in pregnant woman and transplacental antibody transfer at delivery.
According to recent research from the CDC, about 65% of mothers surveyed reported they had not received the seasonal influenza and tetanus, diphtheria and acellular pertussis vaccines before or during pregnancy.
(CNN) — Most pregnant women in the United States don’t get flu and whooping cough vaccines even though the shots are safe and recommended as part of routine prenatal care, a report from the US Centers for Disease Control and Prevention said Tuesday. The report said the low rates of vaccination during pregnancy could put moms-to-be and newborns at greater risk of infection, hospitalization and death. The two vaccinations pass on antibodies to the fetus that provide protection after birth, when babies are too young to be vaccinated. It added that pregnant women have more than double the risk of hospitalization if...
CONCLUSIONS: The revised statements for IIV and Tdap aligned with workshop participants' goals that the product label be evidence-based, with a consistent structure and language that is easily understood by healthcare providers. Emergent methods uncovered stakeholder concerns about the regulatory purpose, content, and evidence used in product labels. Involving healthcare providers in the development and regular updating of product information could prevent interpretations of that information that contribute to vaccine hesitancy. PMID: 31594709 [PubMed - as supplied by publisher]
ConclusionsAlthough maternal Tdap and influenza vaccination coverage increased substantially from 2010 to 2017 among large, geographically diverse U.S. cohorts, coverage remained suboptimal, potentially putting newborns at risk of pertussis and influenza. Strategies to increase maternal vaccination coverage could target women identified to have a reduced likelihood of vaccination: those who are younger, black, residing in rural areas, with multiple gestation, and a prepregnancy inpatient admission.
Abstract Immune status during pregnancy is an important consideration, and all women who are pregnant should be screened for immunity to certain diseases. Women who are pregnant are at higher risk of contracting infections, and many infections can cause serious problems for a growing fetus. For this reason, remaining up-to-date on immunizations throughout life and especially leading up to pregnancy is important. In addition, there are certain vaccines that provide added benefit if given during pregnancy. The Tdap (tetanus toxoid, reduced diphtheria toxoid, acellular pertussis) and inactivated influenza vaccines ca...
In this study, we infected pregnant first parity gilts in their first, second and third trimesters of gestation with PEDV to determine the impact of stage of gestation on generation of maternal B-cell immunity, the gut-MG-sIgA axis and lactogenic immune protection in PEDV challenged piglets. Our goal was to identify innate and adaptive immune factors during pregnancy that influence lymphocyte trafficking, in addition to immune correlates of lactogenic immune protection in neonatal suckling piglets. Understanding the impact of stage of gestation at PEDV infection or exposure on maternal immunity will allow more precise mate...
Inactivated influenza vaccine and diphtheria-tetanus acellular pertussis vaccine are routinely recommended during pregnancy to protect women and their babies from infection. Additionally, the hepatitis B vaccine is recommended for infants within the first week of life; however, little is known about midwives ’ experiences of recommending and delivering these immunisations.
CONCLUSIONS: Sampled OBGYN were largely favorable towards vaccination of pregnant women. As knowledge of official recommendations was identified as a main predictor of appropriate behavior at least for Tdap practice, future educational interventions could eventually improve immunization rates. PMID: 30938116 [PubMed - as supplied by publisher]
This article reviews the current recommendations for vaccination of women during pregnancy. PMID: 30913173 [PubMed - in process]
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