1.19 lymphocytic extracellular signal-related kinase dysregulation in asd

Extracellular signal-regulated kinase (ERK1/2) is a conserved central intracellular signaling cascade involved in many aspects of neuronal development and plasticity. Converging evidence supports the investigation of ERK1/2 activity in ASD. We previously reported enhanced baseline lymphocytic ERK1/2 activation in ASD, and now we extend our work to investigate the early-phase kinetics of lymphocytic ERK1/2 activation in idiopathic ASD.

https://www.jaacap.org/article/S0890-8567(19)31498-4/fulltext?rss=yes

Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 30, 2019 Category: Psychiatry Authors: Craig A. Erickson, Charles Tessier, Christina Gross, Ernest V. Pedapati, Logan K. Wink, Kelli Dominick, Rebecca Shaffer, Paul Horn, Ryan Adams, John Sweeney Source Type: research