Anti-pig antibody in infants: can a genetically-engineered pig heart bridge to allotransplantation?

CONCLUSIONS: Preformed anti-pig antibodies may not be a barrier to heart xenotransplantation in infants, even after cardiac surgery. With adequate immunosuppressive therapy, a triple-knockout pig heart transplant might function successfully as a bridge to allotransplantation.
PMID: 31580857 [PubMed - as supplied by publisher]

Source: The Annals of Thoracic Surgery - September 29, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Li Q, Hara H, Banks CA, Yamamoto T, Ayares D, Mauchley DC, Dabal RJ, Padilla L, Carlo WF, Rhodes LA, Cooper DKC, Cleveland DC Tags: Ann Thorac Surg Source Type: research