The Meaningless Meaning of Mean Heart Dose in Mediastinal Lymphoma in the Modern Radiotherapy Era

ConclusionsIn the management of mediastinal lymphoma, more conformal treatment techniques can lead to more heterogeneous dose distributions across the heart, which translate into weaker relationships between mean heart dose and mean cardiac substructure doses. Consequently, models for assessing the risk of cardiac toxicity after radiotherapy that rely on MHD can be misleading when using modern treatment fields and techniques.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research