MRI-guided laser interstitial thermal therapy for radiation necrosis in previously irradiated brain arteriovenous malformations
Publication date: Available online 14 February 2020Source: Practical Radiation OncologyAuthor(s): Christopher S. Hong, Branden J. Cord, Adam J. Kundishora, Aladine A. Elsamadicy, Jason M. Beckta, Anita Huttner, Veronica L. Chiang, Charles C. MatoukAbstractRadiation necrosis (RN) is a well described complication seen after stereotactic radiosurgery (SRS) for brain arteriovenous malformations (AVM). First-line medical therapies are not always successful in alleviating symptoms and management of some cases may require open surgical resection of the lesion. Surgery is often thought of however as a last resort given its associa...
Source: Practical Radiation Oncology - February 15, 2020 Category: Cancer & Oncology Source Type: research

A novel device for deep-inspiration breath hold (dibh): results from a single institution phase ii clinical trial for left-sided breast cancer patients
ConclusionThe validation of the device within the phase II clinical trial demonstrates that it offers reliable, stable, repeatable, and reproducible breast cancer treatments in DIBH with its dosimetric benefits. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 15, 2020 Category: Cancer & Oncology Source Type: research

The Feasibility and Utility of Cystoscopy-Guided Hydrogel Marker Placement in Patients With Muscle-Invasive Bladder Cancer
ConclusionsCystoscopy-guided placement of hydrogel markers is both safe and feasible for muscle-invasive bladder tumors. Adequate performance for radiation purposes throughout the whole course (implantation, delineation, and positional verification) was 46.7% of all implanted markers, leaving room for improvement. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 13, 2020 Category: Cancer & Oncology Source Type: research

Dose-Escalated Radiation Therapy for Pancreatic Cancer: A Simultaneous Integrated Boost Approach
Publication date: Available online 13 February 2020Source: Practical Radiation OncologyAuthor(s): Eugene J. Koay, Alexander N. Hanania, William A. Hall, Cullen M. Taniguchi, Neal Rebueno, Sten Myrehaug, Katharine L. Aitken, Laura A. Dawson, Christopher H. Crane, Joseph M. Herman, Beth EricksonAbstractPurposeTo provide a detailed description of practical approaches to dose-escalation in pancreatic cancer.Materials/MethodsThe current paper represents an international collaborative effort of radiation oncologists from the MR-linac consortium with expertise in pancreatic dose-escalation. A fifteen fraction hypofractionated int...
Source: Practical Radiation Oncology - February 13, 2020 Category: Cancer & Oncology Source Type: research

Palliative External Beam Radiation Therapy for Hepatocellular Carcinoma With Right Atrial Tumor Thrombus
We describe a case of a patient with a symptomatic HCC RA tumor thrombus who achieved a durable and effective symptomatic response to palliative radiotherapy. We also report our institution’s experience treating 10 HCC patients with RA tumor thrombus with palliative radiotherapy to a median biological effective dose (α/β = 10) of 50.6 Gy (range, 29.3-71.2 Gy). Median follow-up was 5 months. Palliative radiotherapy was well-tolerated, with no grade ≥ 3 acute toxicities. Only one patient experienced in-field progression. Seven patients were alive at least 3 months following radiotherapy, and median overal...
Source: Practical Radiation Oncology - February 13, 2020 Category: Cancer & Oncology Source Type: research

Impact of Audiovisual-Assisted Therapeutic Ambience in Radiation Therapy (AVATAR) on Anesthesia Use, Payer Charges, and Treatment Time in Pediatric Patients
ConclusionsAVATAR introduction decreased anesthesia use in children undergoing RT. More children avoided anesthesia entirely, and fewer needed anesthesia for every treatment, resulting in a reduction in treatment time and savings of nearly $550,000 in approximately 3 years, with minimal perturbation of RT dose delivery. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 13, 2020 Category: Cancer & Oncology Source Type: research

Grateful Recognition of PRO Reviewer Apprentices and Reviewers of the Year
Publication date: Available online 11 February 2020Source: Practical Radiation OncologyAuthor(s): W. Robert Lee (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 12, 2020 Category: Cancer & Oncology Source Type: research

Erratum
Publication date: Available online 28 January 2020Source: Practical Radiation OncologyAuthor(s): (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

Practical Radiation Oncology’s Top 20 Downloads of 2019
Publication date: Available online 6 February 2020Source: Practical Radiation OncologyAuthor(s): W. Robert Lee (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

Effect and Safety of Radiation Therapy Boost to Extramesorectal Lymph Nodes in Rectal Cancer
ConclusionsDespite the well-documented negative prognostic effect of LPN metastasis, we observed promising outcomes for LPN+ patients treated with an additional radiation boost. Our results suggest that radiation therapy boost to clinically involved, unresected LPN is an effective treatment approach with limited toxicity. Additional studies are needed to optimize treatment strategies for this unique patient subset. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

In reply to Dr. Charles Blanke, “The Gift of Dying With Control.”
Publication date: Available online 4 February 2020Source: Practical Radiation OncologyAuthor(s): Brian P. Quaranta (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

In Reply to the American Academy of Dermatology Letter Regarding: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin: An ASTRO Clinical Practice Guideline
Publication date: Available online 5 February 2020Source: Practical Radiation OncologyAuthor(s): Lisa Bradfield, Anna Likhacheva, Joshua H. Petit, Sandra Zaky, Phillip M. Devlin (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

Letter to the Editor: The American Society for Radiation Oncology (ASTRO) Clinical Practice Guidelines on Radiation Therapy for Basal and Squamous Cell Cancers of the Skin
Publication date: Available online 5 February 2020Source: Practical Radiation OncologyAuthor(s): George J. Hruza, Elizabeth M. Billingsley, Marc D. Brown, Paul A. Storrs (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 6, 2020 Category: Cancer & Oncology Source Type: research

Assessing the Variability and Quality of Lung Stereotactic Radiation Therapy Treatment Plans Using a Web-Based Crowdsourcing Platform
ConclusionsThese findings demonstrate the importance of quality assurance to help improve planning and contouring and the value of peer review and comparison. More readily accessible quality evaluation software solutions, such as the one used herein, may help meet this growing need. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - February 1, 2020 Category: Cancer & Oncology Source Type: research

A prospective trial to compare deep inspiratory breath hold (DIBH) with prone breast irradiation
Publication date: Available online 1 February 2020Source: Practical Radiation OncologyAuthor(s): Naamit K. Gerber, Sherry X. Yan, Benjamin A. Levinson, Carmen A. Perez, Indra J. Das, Olivier G. Maisonet, Nelly Huppert, Diana K. No, Jessica Kelley, Neha Mistry, Christine J. Hitchen, Judith D. GoldbergAbstractPurposeTo compare heart and lung doses for adjuvant whole breast irradiation (WBI) between radiation plans generated supine with deep inspiratory breath hold (S-DIBH) and prone with free-breathing (P-FB) and examine the effect of breast volume (BV) on dosimetric parameters.Materials/MethodsPatients with left breast DCIS...
Source: Practical Radiation Oncology - February 1, 2020 Category: Cancer & Oncology Source Type: research

Erratum: A Case of Mistaken Identity: Paget’s Disease of the Bone Causing Cord Compression—Case Report and Review of the Literature
Publication date: Available online 28 January 2020Source: Practical Radiation OncologyAuthor(s): Claire Browne, Adam Mutsaers, Barbara Fisher (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 29, 2020 Category: Cancer & Oncology Source Type: research

Adherence of United States Insurance Payer Policies to American Society of Radiation Oncology (ASTRO) Stereotactic Radiosurgery (SRS) Model Policy
Publication date: Available online 28 January 2020Source: Practical Radiation OncologyAuthor(s): Comron Hassanzadeh, Michael Roach, Keith Rich, Patty Karraker, Clifford Robinson, Jeff Michalski, Stephanie Perkins, Jiayi Huang, Christina Tsien, Christopher AbrahamPurposeMedical necessity of stereotactic radiosurgery (SRS) is non-uniform across insurance policies. American Society for Radiation Oncology (ASTRO) created a model policy based on the consensus of the radiation oncology community to communicate “medically necessary” indications for SRS. We compared current insurance policies for SRS with ASTRO model p...
Source: Practical Radiation Oncology - January 29, 2020 Category: Cancer & Oncology Source Type: research

Stereotactic Image Guided Lung Radiation Therapy for Clinical Early Stage Non-Small Cell Lung Cancer: A Long-Term Report From a Multi-Institutional Database of Patients Treated With or Without a Pathologic Diagnosis
ConclusionsSBRT for clinically diagnosed lung cancers is efficacious in appropriately selected patients, with similar outcomes as those with a pathologic diagnosis. Thorough clinical and radiographic evaluations in a multidisciplinary setting are critical to the management of these patients. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 28, 2020 Category: Cancer & Oncology Source Type: research

Technical Report: Diagnostic Scan Based Planning (DSBP), a method to improve the speed and safety of radiation therapy for the treatment of critically-ill patients
ConclusionThis study demonstrates that it is possible to safely utilize DSBP for the treatment of critically-ill patients. This method has the potential of simplifying the treatment process and improving the speed and safety of treatment. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 28, 2020 Category: Cancer & Oncology Source Type: research

Image Registration and Verification Workshop: A Pilot Study
Publication date: Available online 9 December 2019Source: Practical Radiation OncologyAuthor(s): Laura Padilla, Joshua Dault, Emma FieldsAbstractImage guided radiation therapy is essential to ensure complex treatment plans are delivered safely. Residents in radiation oncology have little to no structured training on how to order or evaluate patient setup imaging. We created a joint image verification workshop for medical and physics residents to learn about setup imaging options available, understand information needed to review patient setup, practice image review, and promote interprofessional collaboration during traini...
Source: Practical Radiation Oncology - January 25, 2020 Category: Cancer & Oncology Source Type: research

Evaluation of the Visibility and Artifacts of 11 Common Fiducial Markers for Image-Guided Stereotactic Body Radiation Therapy in the Abdomen
ConclusionsWe evaluated 11 different fiducials in terms of visibility and artifacts. The results of this study may assist radiation oncologists who seek to maximize contrast, minimize artifacts, and/or balance contrast versus artifacts by fiducial selection. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 25, 2020 Category: Cancer & Oncology Source Type: research

A multidisciplinary consensus recommendation on a synoptic radiation treatment summary: A Commission on Cancer Workgroup report
ConclusionsWe have proposed a consensus template with three sections to meet the needs of a diverse set of consumers. We recommend that providers, professional societies and accreditation bodies with interest in the radiation treatment summary continue collaborative efforts to test, iterate and drive adoption of a synoptic template. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 25, 2020 Category: Cancer & Oncology Source Type: research

Low-Dose Adjuvant Cylinder Brachytherapy for Endometrioid Endometrial Cancer
Publication date: Available online 26 November 2019Source: Practical Radiation OncologyAuthor(s): Gabriela M. Alban, Daniela L. Buscariollo, Teresa Cheng, Jennifer Pretz, Betty Krechmer, Ivan Buzurovic, Lisa Singer, Martin King, Larissa LeeAbstractPurposeOur purpose was to evaluate outcomes and sites of failure for women with early stage endometrial adenocarcinoma treated with adjuvant high-dose-rate (HDR) vaginal brachytherapy (VB) with a low dose scheme.Methods and MaterialsRetrospective review identified 318 patients with International Federation of Gynecology and Obstetrics (FIGO) stage I-II endometrioid endometrial ca...
Source: Practical Radiation Oncology - January 23, 2020 Category: Cancer & Oncology Source Type: research

Coregistration of Magnetic Resonance and [18F] Fludeoxyglucose–Positron Emission Tomography Imaging for Stereotactic Radiation Therapy Planning: Case Report in a Previously Irradiated Brain Metastasis With Recurrent Tumor and Radiation Necrosis
Publication date: Available online 29 November 2019Source: Practical Radiation OncologyAuthor(s): Robert A. Scranton, Saeed Sadrameli, Edward Brian Butler, Andrew Farach, Hui-Chuan Wang, Bin S. Teh, Ivo W. Tremont-Lukats, Steve H. Fung, Paolo Zanotti-Fregonara, Robert C. RostomilyAbstractStereotactic radiosurgery (SRS) or radiotherapy (SRT) is commonly used to treat brain metastasis (BM). While effective in achieving tumor control, a significant number of BM patients exhibit lesion growth on follow-up MR imaging after SRS which cannot reliably distinguish between tumor growth, radiation necrosis (RN) or a mixture of both. ...
Source: Practical Radiation Oncology - January 23, 2020 Category: Cancer & Oncology Source Type: research

Improvements in Physician Clinical Workflow Measures After Implementation of a Dashboard Program
Publication date: Available online 5 December 2019Source: Practical Radiation OncologyAuthor(s): Gregory C. Stachelek, Todd McNutt, Carol B. Thompson, Koren Smith, Theodore L. DeWeese, Daniel Y. SongAbstractPurposeTo determine whether a combination of data-driven, personalized feedback and implementation of a graduated, sequential intervention model improved key measures of physician workflow and quality in radiation treatment planning.Methods and MaterialsAll radiation oncologists across 3 facilities at a single academic institution were prospectively evaluated on 5 predefined metrics of timeliness and accuracy in the tre...
Source: Practical Radiation Oncology - January 23, 2020 Category: Cancer & Oncology Source Type: research

Who Benefits From a Prostate Rectal Spacer? Secondary Analysis of a Phase III Trial
Publication date: Available online 21 January 2020Source: Practical Radiation OncologyAuthor(s): Thomas J. Quinn, Stephanie Daignault-Newton, Walter Bosch, Neil Mariados, John Sylvester, Dhiren Shah, Eric Gross, Richard Hudes, David Beyer, Steven Kurtzman, Jeffrey Bogart, R. Alex Hsi, Michael Kos, Rodney Ellis, Mark Logsdon, Shawn Zimberg, Kevin Forsythe, Hong Zhang, Edward Soffen, Patrick FranckeAbstractPurpose/Objective(s)Previously a phase III trial of a hydrogel rectal spacer during prostate RT found decreased toxicity and a clinically significant improvement in bowel quality of life (QOL) at 3-years by Expanded Prosta...
Source: Practical Radiation Oncology - January 22, 2020 Category: Cancer & Oncology Source Type: research

Computed Tomography to Cone Beam Computed Tomography Deformable Image Registration for Contour Propagation Using Head and Neck, Patient-Based Computational Phantoms: A Multicenter Study
ConclusionsThe performance of the systems proved to be image quality specific, depending on the DVF type and only partially on the platforms. All systems proved to be robust against image artifacts and noise, except the demon-based software. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 19, 2020 Category: Cancer & Oncology Source Type: research

Patterns of Failure Observed in the 2-Step Institution Credentialing Process for NRG Oncology/Radiation Therapy Oncology Group 1005 (NCT01349322) and Lessons Learned
ConclusionsThe review of the benchmark and rapid review QA submissions indicates that acceptable variations or unacceptable deviations for the ipsilateral lung and heart dose constraints were the most commonly observed cause of benchmark QA failure, and unacceptable deviations in target contouring, rather than normal structure contouring, were the most common cause of rapid review QA failure. These findings suggest that a rigorous QA process is necessary for high quality and homogeneity in radiation therapy in multi-institutional trials of breast cancer to ensure that the benefits of radiation therapy far outweigh the risk...
Source: Practical Radiation Oncology - January 19, 2020 Category: Cancer & Oncology Source Type: research

Framework for Evaluation of Automated Knowledge-Based Planning Systems Using Multiple Publicly Available Prostate Routines
Publication date: Available online 5 December 2019Source: Practical Radiation OncologyAuthor(s): Xenia Ray, Robert Kaderka, Sebastian Hild, Mariel Cornell, Kevin L. MooreAbstractPurposeTo establish a framework for the evaluation of knowledge-based planning routines that empowers new adopters to select systems that best match their clinical priorities. We demonstrate the power of this framework using 4 publicly available prostate routines.Methods and MaterialsFour publicly available prostate routines (CCMB, Miami, UCSD, WUSTL) were automatically applied across a 25-patient cohort using Eclipse scripting and a PTV prescripti...
Source: Practical Radiation Oncology - January 19, 2020 Category: Cancer & Oncology Source Type: research

A Radiation Oncology–Specific Automated Trigger Indicator Tool for High-Risk, Near-Miss Safety Events
ConclusionsThe radiation oncology–specific automated trigger tool performed modestly and identified additional treatment courses with near-miss events. Radiation oncology trigger tools deserve further exploration. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 18, 2020 Category: Cancer & Oncology Source Type: research

Educators’ Perspectives on the Association of Residents in Radiation Oncology Survey of Residents’ Concerns
Publication date: Available online 29 November 2019Source: Practical Radiation OncologyAuthor(s): Rahul D. Tendulkar, Trevor J. Royce, Kenneth R. Olivier, Emma C. Fields, Daniel W. Golden, Neha Vapiwala (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 18, 2020 Category: Cancer & Oncology Source Type: research

Minimizing General Anesthetic Use in Pediatric Radiation Therapy
Publication date: Available online 10 December 2019Source: Practical Radiation OncologyAuthor(s): Stephanie M. Ntoukas, Tatiana Ritchie, Susan Awrey, David C. Hodgson, Normand Laperriere, Ryan Yee, Vijay Ramaswamy, Barbara-Ann Millar, Nathan Becker, Derek S. TsangAbstractPurposeAt our institution, a multifaceted approach is used to reduce general anesthetic (GA) use for children receiving photon radiation therapy (RT) as standard-of-care treatment. The purpose of this study was to evaluate the effectiveness of our methods.Methods and MaterialsPatients treated as part of the pediatric radiation therapy program from 2010 to ...
Source: Practical Radiation Oncology - January 18, 2020 Category: Cancer & Oncology Source Type: research

Cystic Lymph Node Metastases From HPV-Associated Squamous Cell Carcinoma of the Anal Canal
Publication date: Available online 19 December 2019Source: Practical Radiation OncologyAuthor(s): Allison E. Garda, Shannon P. Sheedy, Michael G. Haddock, Christopher L. Hallemeier (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 18, 2020 Category: Cancer & Oncology Source Type: research

Impact of Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) on Anesthesia Use, Payer Charges, and Treatment Time in Pediatric Patients
ConclusionsXXX introduction decreased anesthesia use in children undergoing radiotherapy; more avoided anesthesia entirely, and fewer needed it for every treatment. This resulted in a reduction in treatment time, and savings of nearly $550,000 in approximately 3 years, with minimal perturbation of radiotherapy dose delivery. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 13, 2020 Category: Cancer & Oncology Source Type: research

Palliative external beam radiotherapy for hepatocellular carcinoma with right atrial tumor thrombus
We describe a case of a patient with a symptomatic HCC RA tumor thrombus who achieved a durable and effective symptomatic response to palliative radiotherapy. We also report our institution’s experience treating 10 HCC patients with RA tumor thrombus with palliative radiotherapy to a median biological effective dose (α/β = 10) of 50.6 Gy (range, 29.3-71.2 Gy). Median follow-up was 5 months. Palliative radiotherapy was well-tolerated, with no grade ≥ 3 acute toxicities. Only one patient experienced in-field progression. Seven patients were alive at least 3 months following radiotherapy, and median overal...
Source: Practical Radiation Oncology - January 10, 2020 Category: Cancer & Oncology Source Type: research

A 15-Year Profile of U.S. Radiation Oncology Residency Growth by Geographic Region, Metropolitan Size, and Program Size
ConclusionsThere has been a major increase in the number of RO residency programs and positions over the past 15 years. Growth is occurring in every major category but there are differences in magnitude within each category. This information can inform future decisions about RO training programs in the United States. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - January 9, 2020 Category: Cancer & Oncology Source Type: research

Advantages of Radiation Therapy Simulation with 0.35 Tesla Magnetic Resonance Imaging for Stereotactic Ablation of Spinal Metastases
Publication date: Available online 26 November 2019Source: Practical Radiation OncologyAuthor(s): Benjamin Spieler, Stuart E. Samuels, Ricardo Llorente, Raphael Yechieli, John Chetley Ford, Eric A. MellonAbstractThe hybrid 0.35T magnetic resonance imaging (MRI) and radiation therapy system functions in part as a simulation platform for treatment planning. We have found that the images generated are particularly helpful for planning of stereotactic radiation therapy for spinal metastases. Advantages include the following: (1) Low-field MRI mitigates magnetic susceptibility artifacts caused by spinal hardware. (2) Volumetric...
Source: Practical Radiation Oncology - January 4, 2020 Category: Cancer & Oncology Source Type: research

Masthead/Sub page
Publication date: January–February 2020Source: Practical Radiation Oncology, Volume 10, Issue 1Author(s): (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Editorial Board
Publication date: January–February 2020Source: Practical Radiation Oncology, Volume 10, Issue 1Author(s): (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Table of Contents
Publication date: January–February 2020Source: Practical Radiation Oncology, Volume 10, Issue 1Author(s): (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Error Types and Associations of Clinically Significant Events Within Food and Drug Administration Recalls of Linear Accelerators and Related Products
Publication date: January–February 2020Source: Practical Radiation Oncology, Volume 10, Issue 1Author(s): Vikram Jairam, Holly M. Lincoln, Derek W. Brown, Henry S. Park, Suzanne B. EvansAbstractPurposeMedical devices in radiation therapy undergo a complex process of Food and Drug Administration (FDA) approval. Little is known about which processes within the radiation therapy medical device industry are most prone to events involving wrong dose, volume, or targeting in radiation therapy treatment.Methods and MaterialsWe carried out a retrospective analysis of the United States FDA Medical Device Recalls database for ...
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Dose-Effect Analysis of Early Changes in Orbital Bone Morphology After Radiation Therapy for Rhabdomyosarcoma
ConclusionsDespite the dosimetric precision of proton therapy, orbital asymmetry will develop after>40 GyRBE to multiple bones of the orbital rim. These data may be used to guide treatment planning and counsel patients on expected cosmesis. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Using Robust Optimization for Skin Flashing in Intensity Modulated Radiation Therapy for Breast Cancer Treatment: A Feasibility Study
ConclusionUsing robust optimization for skin flash in breast intensity modulated radiation therapy planning is feasible. Further investigation is warranted to confirm the clinical effectiveness of this novel approach. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 31, 2019 Category: Cancer & Oncology Source Type: research

The Effectiveness of Intra-Operative Clip Placement in Improving Radiotherapy Boost Targeting Following Oncoplastic Surgery
ConclusionsIn oncoplastic surgery patients, intra-operative placement of surgical clips is beneficial and effective in improving the delineation of the tumor bed cavity for the radiotherapy boost. Four clips are necessary and sufficient for accurate boost targeting following lumpectomy with oncoplastic reconstruction. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 21, 2019 Category: Cancer & Oncology Source Type: research

Cystic lymph node metastases from HPV-associated squamous cell carcinoma of the anal canal
Publication date: Available online 19 December 2019Source: Practical Radiation OncologyAuthor(s): Allison E. Garda, Shannon P. Sheedy, Michael G. Haddock, Christopher L. Hallemeier (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 21, 2019 Category: Cancer & Oncology Source Type: research

The feasibility and utility of cystoscopy-guided hydrogel marker placement in patients with muscle invasive bladder cancer
ConclusionCystoscopy-guided placement of hydrogel markers is both safe and feasible for muscle-invasive bladder tumors. Adequate performance for radiation purposes throughout the whole course (implantation, delineation and positional verification) was 46.7% of all implanted markers, leaving room for improvement. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 21, 2019 Category: Cancer & Oncology Source Type: research

Impact and safety of radiotherapy boost to extra-mesorectal lymph nodes in rectal cancer
ConclusionDespite the well documented negative prognostic impact of LPN metastasis, we observed promising outcomes for LPN+ patients treated with an additional radiation boost. Our results suggest that radiotherapy boost to clinically involved, un-resected LPN is an effective treatment approach with limited toxicity. Additional studies are needed to optimize treatment strategy for this unique patient subset. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 21, 2019 Category: Cancer & Oncology Source Type: research

Assessing the Variability and Quality of Lung Stereotactic Radiotherapy Treatment Plans using a Web-Based Crowdsourcing Platform
ConclusionsThese findings demonstrate the importance of quality assurance to help improve planning and contouring, as well the value of peer review and comparison. More readily accessible quality evaluation software solutions, such as the one used here, may be poised to help meet this growing need. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Stereotactic image-guided lung radiotherapy (SBRT) for clinical early-stage NSCLC: A long-term report from a multi-institutional database of patients treated with or without a pathologic diagnosis.
ConclusionsSBRT for clinically diagnosed lung cancers is efficacious in appropriately selected patients, with similar outcomes as those with pathologic diagnosis. Thorough clinical and radiographic evaluation in a multidisciplinary setting is critical to the management of these patients. (Source: Practical Radiation Oncology)
Source: Practical Radiation Oncology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Minimizing general anaesthetic use in paediatric radiation therapy: Reducing GA in paediatric RT
Publication date: Available online 10 December 2019Source: Practical Radiation OncologyAuthor(s): Stephanie M. Ntoukas, Tatiana Ritchie, Susan Awrey, David C. Hodgson, Normand Laperriere, Ryan Yee, Vijay Ramaswamy, Barbara-Ann Millar, Nathan Becker, Derek S. TsangAbstractBackgroundAt our institution, a multi-faceted approach is used to reduce general anesthetic (GA) use for children receiving photon radiation therapy (RT), as standard-of-care treatment. The purpose of this study was to evaluate the effectiveness of our methods.MethodsPatients treated as part of the paediatric radiotherapy program from 2010-2018 were retros...
Source: Practical Radiation Oncology - December 10, 2019 Category: Cancer & Oncology Source Type: research