P.227Secondary clinical outcomes of spinal surgery and satisfaction in patients with spinal muscular atrophy (SMA) II and non-ambulant III

Scoliosis is a highly prevalent feature of SMA and surgery is frequently required. Studies in small cohorts have reported a positive impact of spinal surgery on respiratory function, while limited data are available on motor function, weight gain, post-surgical skeletal pain and satisfaction. We retrospectively reviewed the notes of 33 patients (26 SMA II, 7 non-ambulant SMA III) who successfully underwent spinal fusion (25), magnetic (4) or traditional (4) growth rods followed by final growth spinal fusion (3) at Great Ormond Street Hospital-London.

Source: Neuromuscular Disorders - September 30, 2019 Category: Neurology Authors: C. Brusa, J. De Graaf, A. Manzur, M. Main, E. Milev, M. Iodice, D. Ramsey, S. Tucker, T. Ember, R. Nadarajah, F. Muntoni, M. Scoto Source Type: research