The characteristics of FLT3 mutations in Chinese de novo adolescent and adult ALL patients

Activating mutations in FLT3 are frequent in acute myeloid leukemia (AML) and have important prognostic and therapeutic implications. Meanwhile, FLT3 aberrations have been detected in a smaller fraction of acute lymphoblastic leukemia (ALL), and their prognostic value are not well established. Therefore, we assessed the FLT3 mutation in Chinese adolescent and adult ALL patients.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 30, 2019 Category: Hematology Authors: Zhen Shen, Xiao-Ling Chu, Rong-Xian Wang, Jin-Li Li, Meng-Yao Liu, Yi-Yu Xie, Chao Wang, Rong Han, Jing-Qiu Yu, Jun Wang, Tao Tao, Hong-Jie Shen, Su-Ning Chen, De-Pei Wu, Qiao-Cheng Qiu, Song-Bai Liu, Sheng-Li Xue Tags: Original Study Source Type: research