An integrative DNA methylation model for improved prognostication of postsurgery recurrence and therapy in prostate cancer patients.

CONCLUSIONS: We have identified and validated a novel integrative gene model as an independent prognosticator of BCR and demonstrated its association with late BCR. These patients require more long-term postsurgical monitoring and could be spared the comorbidities of adjuvant therapies.
PMID: 31558364 [PubMed - as supplied by publisher]

Source: Urologic Oncology - September 23, 2019 Category: Urology & Nephrology Authors: Jeyapala R, Kamdar S, Olkhov-Mitsel E, Savio AJ, Zhao F, Cuizon C, Liu RS, Zlotta A, Fleshner N, van der Kwast T, Bapat B Tags: Urol Oncol Source Type: research