Thyroid dose ‐volume thresholds for the risk of radiation‐related hypothyroidism in nasopharyngeal carcinoma treated with intensity‐modulated radiotherapy—A single‐institution study

ConclusionWe recommendV25Gy ≤ 60%,V35Gy ≤ 55%, andV45Gy ≤ 45% as the “stringent” DVH line, andV25Gy >  95%,V35Gy >  90%, andV45Gy >  75% as the “inhibition” DVH line, under the precondition of not compromising the target coverage. These findings could help in the design of individual treatment plans and, eventually, to lowering of HT prevalence.

Source: Cancer Medicine - September 26, 2019 Category: Cancer & Oncology Authors: Cheng ‐Long Huang, Hong‐Wen Tan, Rui Guo, Yuan Zhang, Hao Peng, Liang Peng, Ai‐Hua Lin, Yan‐Ping Mao, Ying Sun, Jun Ma, Ling‐Long Tang Tags: ORIGINAL RESEARCH Source Type: research