Ischemic Stroke Following Ergotamine Overdose

The use of ergotamine in the treatment of migraine has become disputed because of its significant side effects, such as arterial vasospasm particularly affecting the peripheral arteries.1 However, there is conflicting evidence about the effect of ergotamine on cerebral blood flow.2-4 At present, ergotamine continues to be utilized, albeit off-license, for the treatment of refractory migraine in pediatric patients.5 Yet, there is a lack of evidence supporting ergotamine's utility and safety in migraine treatment.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Clinical Letter Source Type: research