Impact of the physical activity on the phenotype of circulating monocytes and the biological characteristics of the carotid plaque

Atherosclerosis is accompanied by a low-grade inflammation which mobilizes the classical, intermediate and non-classical circulating monocytes. It was shown that an accumulation of leucocytes supports the development of intraplaque hemorrhage (IPH), making the plaque vulnerable, exposed to rupture and thrombosis. Moreover, the elevation of the rate of intermediate monocytes is associated with an increase in cardiovascular mortality and ischemic stroke. The benefit of endarterectomy (CE) remains discussed in the patients without stroke.

Source: Annals of Vascular Surgery - September 24, 2019 Category: Surgery Authors: Mathilde Mura, Mich èle Weiss, Nellie Della Schiava, Marine Bordet, Patrick Lermusiaux, Antoine Millon, Vincent Pialoux Tags: Abstracts Presented to the French Society for Vascular and Endovascular Surgery Source Type: research