Effect of Radical Surgery for Advanced Adenocarcinoma of Esophagogastric Junction on Perioperative Cellular Cell Immunity.
Conclusion: The change in the CD4+PD-1+ T lymphocyte ratio may likely reflect the cellular immunity status of the perioperative period. PMID: 31533488 [PubMed - as supplied by publisher]
ConclusionWhen TG allows obtaining tumor-free resection margins, this approach should be preferred to SPO.
This article reviews the history of surgical EGJ cancer treatment and current surgical strategies from a Western perspective. PMID: 31245158 [PubMed]
Conclusion: Single-stage radical resection of the oesophagus and a cephalic duodeno-pancreatectomy can be more considered for synchronous cancers even in elderly patient. PMID: 31230557 [PubMed - as supplied by publisher]
the use of endoscopic sleeve gastrostomy has received much attention in recent years. However, sleeve gastrectomy (SG) has been reported to worsen gastroesophageal reflux disease (GERD), a major risk factor for Barrett ’s esophagus (BE) and esophageal adenocarcinoma (EAC). The incidence of GERD and BE post SG has not been well reported.
In response to the obesity epidemic, rates of bariatric surgery have increased, particularly laparoscopic sleeve gastrectomy, which is now the most commonly performed bariatric surgery worldwide. Laparoscopic sleeve gastrectomy excises the greater curvature of the stomach, resulting in a restricted tubular reservoir approximately 25% of its native volume. Although technically simple, safe, and effective for weight loss, sleeve gastrectomy is associated with increased health care utilization costs secondary to multiple known serious adverse events (SAEs), and increased prevalence of worsened or de novo GERD with unknown ass...
n R Abstract The updated German S3 guidelines recommend transthoracic subtotal esophagectomy with 2‑field lymphadenectomy for surgical treatment of esophageal cancer in patients with squamous cell carcinoma and adenocarcinoma of the esophagogastric (AEG type I) junction of the middle and lower third. For AEG type III transhiatal extended total gastrectomy with distal esophageal resection is favored. Patients with AEG type II can be treated by both procedures under the prerequisite that an R0 resection can be achieved. A limited resection of the distal esophagus and the proximal stomach can on...
ConclusionsThis study represents the first prospective feasibility evaluation of sentinel lymph node sampling for early gastric cancer in North America with promising preliminary results. The dual tracer method was superior to single agent blue dye in identifying sentinel nodal basins. Considerable further study is necessary to verify the safety and utility of SLN mapping in North American patients with early gastric adenocarcinoma.
We describe the new technique as: distal gastrectomy preserving the gastroepiploic vessels, Roux-en-Y gastrojejunostomy and thoracoscopic Ivor Lewis esophagectomy with chest anastomosis. Outcomes: Three patients accepted the surgery and recovered well without any complications. The patients did not undergo any postoperative adjuvant therapy and was doing well without any recurrence till date (23 months, 12 months, 6 months separately). Lessons: This procedure was less invasive and easier to perform for synchronous early-stage gastric cardiac cancer and middle or lower third thoracic esophageal cancer. We recommend th...
ConclusionTHX-ABD can be performed with high rates of R0 resections and with low in-hospital mortality. Long-term survival rate was not better compared with less extensive surgical procedures.Graphical abstract
Background: Barrett's Esophagus (BE),common in individuals with gastroesophageal reflux disease (GERD), pre-disposes the affected individual to the potential development of intestinal metaplasia, dysplasia and esophageal adenocarcinoma. Due to physiologic changes incurred post Laparoscopic Sleeve Gastrectomy (LSG), there is an increased risk of BE development, or progression in patients with active GERD. Because of this, many surgeons consider a patient who has BE to be contraindicated for LSG surgery.