Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia

The microsomal triglyceride transport protein (MTTP) is critical for assembly and secretion of apolipoprotein B (apoB)-containing lipoproteins and is most abundant in the liver and intestine. Surprisingly, MTTP is also expressed in the heart. Here we tested the functional relevance of cardiac MTTP expression.

Source: Journal of Molecular and Cellular Cardiology - September 14, 2019 Category: Cytology Authors: Martina Klevstig, Muhammad Arif, Maria Mannila, Sara Svedlund, Ismena Mardani, Marcus St åhlman, Linda Andersson, Malin Lindbom, Azra Miljanovic, Anders Franco-Cereceda, Per Eriksson, Anders Jeppsson, Li-Ming Gan, Malin Levin, Adil Mardinoglu, Ewa Ehrenb Source Type: research