2009 H1N1 swine flu deadliest for those age 65 and younger
IRVINE, Calif., May 24 (UPI) -- There were 53,692 pneumonia and influenza U.S. deaths in the 2009 H1N1 swine flu pandemic and the hardest hit were those age 65 and younger, researchers say.
Publication date: Available online 16 January 2019Source: Academic PediatricsAuthor(s): Richard G. Bachur, Kenneth A. Michelson, Mark I. Neuman, Michael C. MonuteauxABSTRACTObjectivesAs both fever and pneumonia can be are associated with tachypnea, we investigated the relationship between body temperature and respiratory rate (RR) in young children and whether temperature-adjusted RR enhances the prediction of pneumonia.MethodsIn this retrospective cross-sectional analysis of 91,429 children
Authors: Y D, Manjrekar PA, Adhikari P, M C, Ms R Abstract Vitamin D, a steroid hormone is primarily known for its role in calcium and bone mineral homeostasis. Over the years, vitamin D has been implicated in various non-skeletal diseases. The extraskeletal phenomenon can be attributed to the presence of vitamin D receptors (VDRs) in almost all cells and identification of 1-α hydroxylase in extrarenal tissues. The vitamin D deficiency (VDD) pandemic was globally reported with increasing evidence and paralleled the prevalence of diabetes, obesity and cardiovascular diseases (CVDs). A dependent link was propos...
CONCLUSIONS Patients with COP with solitary mass form are more susceptible to hemoptysis and the mass is prone to necrosis. Vascular bundles, exudation around the mass, interstitial lymphocyte infiltration, and mediastinal lymph node enlargement are common features. PMID: 30648699 [PubMed - in process]
Conclusion: There was a persistently high systemic vascular resistance index in cold shock patients that influenced the stroke volume index, cardiac index, and velocity time integral. The use of echocardiograms for hemodynamic measurements is important in pediatric septic shock patients to adjust dilators, and vasopressor doses and achieve resuscitation targets in a timely manner.
A new cell-based seasonal influenza vaccine has been issued marketing approval by the European Commission and will be available for the 2019/2020 flu season.
A new study concludes that some of the species of bacteria in our airways, called the respiratory microbiome, can protect us against the influenza virus.
Amie J. Eisfeld, David J. Gasper, M. Suresh, Yoshihiro Kawaoka
Influenza A virus (IAV) infection is often followed by secondary bacterial lung infection, which is a major reason for severe, often fatal pneumonia. Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains such as USA300 cause particularly severe and difficult-to-treat cases of IAV-associated pneumonia. CA-MRSA strains are known to produce extraordinarily large amounts of phenol-soluble modulin (PSM) peptides, which are important cytotoxins and proinflammatory molecules that contribute to several types of S. aureus infection. However, their potential role in pneumonia has remained elusive. We det...
Conclusion Prevention of swine influenza has 3 components: prevention in swine, prevention of transmission to humans, and prevention of its spread among humans. Because of limited treatment options, high risk for secondary infection, and frequent need for intensive care of individuals with H1N1 pneumonia, environmental control, including vaccination of high-risk populations and public education are critical to control of swine influenza out breaks.
CONCLUSIONS: We recommend that patients with severe influenza A/H1N1 pneumonitis and respiratory failure be administered DVT prophylaxis in particular if there are additional risk factors for TVE. Further prospective studies on the relationship of influenza A/H1N1 and VTE are needed. PMID: 26365372 [PubMed - as supplied by publisher]