Functional electrical stimulation (FES) for children and young people with cerebral palsy

Evidence for functional electrical stimulation (FES) as a treatment option in adult neurological conditions has grown over the last 25 years. Children and young people with neurological conditions can also benefit from FES treatments but there are gaps in clinical knowledge, awareness and evidence which need addressing. Some of the known benefits of FES include safe walking with facilitation and exercise of ‘normal’ movement, muscle strengthening, joint range and proprioceptive improvements as well as spasticity reduction.
Source: Paediatrics and Child Health - Category: Pediatrics Authors: Tags: Personal practice Source Type: research

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Publication date: Available online 12 October 2019Source: Neuroscience LettersAuthor(s): Niamh B. McNamara, Veronique E. MironAbstractPerinatal brain injury (PBI) to the developing white matter results in hypomyelination of axons and can cause long-term motor and cognitive deficits e.g. cerebral palsy. There are currently no approved therapies aimed at repairing the white matter following insult, underscoring the need to investigate the mechanisms underlying the pathogenesis of PBI. Microglia have been strongly implicated, but their function and heterogeneity in this context remain poorly understood, posing a barrier to th...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Bilateral cerebral palsy (BCP) is a common movement disorder in children, which often results in lifelong motor disability. One main symptom of BCP is the limitation of hand function in everyday activities. However, the neuroanatomical basis of this prominent hand impairment is yet to discover. Recent advances mainly focus on the lesions of BCP, but the views on the atypical development of cortical parcellations are extremely lacking. Here, in our study, neuroimaging with network analysis was employed to evaluate the changes of structural covariance networks (SCNs) in BCP children. We aimed to elucidate the alteration of S...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Delayed cord clamping improves health of babies born too early: updated Cochrane ReviewThis updated Cochrane systematic review   finds that delayed, rather than early, cord clamping may reduce the risk of death before discharge for babies born preterm.The authors set out to determine if delayed cord clamping or umbilical cord milking improves the health outcomes for babies born before 37 weeks'gestation. These interventions were compared with early cord clamping.Babies born before 37 weeks, or preterm, have poorer health outcomes than babies born at term, particularly if they are born before 32 weeks. They can experie...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
CONCLUSION: The results support the impact of resistive therapy on gait improvement, especially in terms of the gait speed and step cadence parameters. PMID: 31588984 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
Abstract BACKGROUND: Cerebral palsy (CP) is the most common cause of physical disabilities in children in high-income countries. Spasticity is the most common motor disturbance in CP. Botulinum toxin type A (BoNT-A) is considered the first-line treatment for focal spasticity in people with CP. OBJECTIVES: To evaluate the effectiveness and safety of BoNT-A compared to other treatments used in the management of lower limb spasticity in children with CP. SEARCH METHODS: We searched CENTRAL, PubMed, four other databases, and two trial registers in October 2018. We also searched the reference lists of relevan...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
by Carmichael F. Ong, Thomas Geijtenbeek, Jennifer L. Hicks, Scott L. Delp Deficits in the ankle plantarflexor muscles, such as weakness and contracture, occur commonly in conditions such as cerebral palsy, stroke, muscular dystrophy, Charcot-Marie-Tooth disease, and sarcopenia. While these deficits likely contribute to observed gait pathologies, determining cause-effect relationships is difficult due to the often co-occurring biomechanical and neural deficits. To elucidate the effects of weakness and contracture, we systematically introduced isolated deficits into a musculoskeletal model and generated simulations of walk...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
Conclusion: Vibratory platform, gait training, electrical stimulation, and transcranial stimulation were effective to improve spatiotemporal gait parameters, especially velocity in children with cerebral palsy. Implication for rehabilitation Improvement and maintenance of gait of children with cerebral palsy is a great challenge to rehabilitation professionals Vibratory platform, gait training, electrical stimulation, and transcranial stimulation improve gait parameters. Isolated strength training was not effective to improve gait parameters in Cerebral Palsy. Long-term effect of most techniques on gait parameters until un...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
by Drew Rosielle (@drosielle)A Series of Observations on Opioids By a Palliative Doc Who Prescribes A Lot of Opioids But Also Has Questions.This is the 5th post in a series about opioids, with a focus on how my thinking about opioids has changed over the years. See also:Part 1 – Introduction, General Disclaimers, Hand-Wringing, and a Hand-Crafted Graph.Part 2 – We Were Wrong 20 years Ago, Our Current Response to the Opioid Crisis is Wrong, But We Should Still Be Helping Most of our Long-Term Patients Reduce Their Opioid DosesPart 3 – Opioids Have Ceiling Effects, High-Doses are Rarely Therapeutic, and Ano...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Care Tags: opioid pain rosielle The profession Source Type: blogs
This study is a case report of a child who was diagnosed ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Publication date: Available online 3 October 2019Source: CytotherapyAuthor(s): Joseph Aziz, Gary Liao, Zach Adams, Mina Rizk, Risa Shorr, David S. AllanAbstractClinical use of umbilical cord blood (UCB) for novel indications in regenerative therapy continues to rise, however, whether new indications are proven is less clear. An updated systematic search of the literature, focusing only on controlled clinical studies, is needed to properly assess potential efficacy. After updating our systematic search to April 1, 2018 (PROSPERO protocol CRD42016040157), a total of 16 studies were identified that addressed the treatment of ...
Source: Cytotherapy - Category: Cytology Source Type: research
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