Cancers, Vol. 11, Pages 1359: Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells

In conclusion, allosteric AKT inhibitors represent a promising class of drugs for chemoprevention and chemotherapy of cancers with E-cadherin loss.

Source: Cancers - September 12, 2019 Category: Cancer & Oncology Authors: Nicola Bougen-Zhukov Yasmin Nouri Tanis Godwin Megan Taylor Christopher Hakkaart Andrew Single Tom Brew Elizabeth Permina Augustine Chen Michael A. Black Parry Guilford Tags: Article Source Type: research