Combination of both primary pure squamous cell carcinoma (SCC) and conventional invasive lobular carcinoma (ILC) in the same breast; A rare case report and review of the literature

ConclusionPrimary pure SCC of the breast is a rare malignancy which has a rapid rate of growth and a poor prognosis, moreover, ILC has high metastatic rate. Due to rarity of such condition and uncertain treatment modality it should be kept in mind its presence to allow choosing adequate therapy.
Source: Human Pathology: Case Reports - Category: Pathology Source Type: research

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Abstract In this work, the as-prepared V2O5 nanobelts can sensitively quench the fluorescence of nitrogen-doped carbon dots (N-CDs) based on the inner filter effect (IFE). In the presence of ascorbic acid (AA), the fluorescence of N-CDs can recover through the redox reaction between V2O5 nanobelts and AA. Meanwhile, in the presence of both alkaline phosphatase (ALP) and ascorbyl-2-phosphate (AAP), the fluorescence of N-CDs can also restore since AAP can be hydrolyzed into AA by ALP. Under optimum conditions, the linear range for AA is from 0.01 to 2.5 μM with a detection limit of 3 nM and that for ALP is fr...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC07253E, CommunicationXuehan Yin, Ting Hou, Bingzheng Huang, Limin Yang, Feng Li We developed an aptamer recognition-trigged label-free homogeneous electrochemical biosensing method for highly selective and ultrasensitive detection of cancer-derived exosomes. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
ConclusionsPhysical and psychological functioning, pain, fatigue and appetite loss had prognostic significance above and beyond clinical predictors in CRC. Routine monitoring of these PROs may allow earlier detection and amelioration of problems, which may improve quality of life and perhaps extend survival. More research is needed to determine prognostic value of PROs in early-stage CRC, and prognostic significance of changes in PRO scores.
Source: Quality of Life Research - Category: Health Management Source Type: research
ConclusionsThe experience of changes in taste was common yet highly variable in its presentation and resultant changes in food preferences. Taste changes did not always resolve soon after treatment completion. Future research should identify ways to manage this symptom in pediatric cancer patients.
Source: Quality of Life Research - Category: Health Management Source Type: research
Synchronous cancer in patients with abdominal aortic aneurysm (AAA) increases their morbidity and mortality after AAA repair. However, little is known about the history of cancer in AAA patients and its impact on mortality after AAA repair. We analyzed the incidence and type of cancer history in patients who underwent AAA repair and difference in short- and long-term mortality.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
This review highlights new radiological technologies with potential for improving oncologic management and reducing toxicity of treatment for older adults with cancer.Age and Ageing
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news
What knowledge have we gained regarding the presentation and management of renal cell carcinoma in young patients?Current Opinion in Urology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Urology Journal Article Source Type: news
Roche today announced that the Phase III IMbrave150 study, evaluating Tecentriq ® (atezolizumab) in combination with Avastin® (bevacizumab) as a treatment for people with unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy, met both of its co-primary endpoints demonstrating statistically significant and clinically meaningful improvements i n overall survival (OS) and progression-free survival (PFS) compared with standard-of-care sorafenib.
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
AbstractMetastatic breast carcinoma to the urinary bladder is rare. Eleven cases of metastatic breast carcinoma to the bladder are described in this report, including one case with a tumor to tumor metastasis. The patients ranged from 51 to 83  years of age. The time intervals between the diagnosis of primary breast cancer and the occurrence of bladder metastases ranged from 41 to 336 months. There were seven cases of invasive ductal carcinoma and four cases of invasive lobular carcinoma. In one case, a lobular carcinoma of the breast m etastasized to a concurrent squamous cell carcinoma of the bladder. The immun...
Source: Virchows Archiv - Category: Pathology Source Type: research
This study redefines age extreme in breast pathology to better correlate with current patient demographics, and provides characteristics of breast cancer in this population. Little information exists about the breast cancer in extremely old women. This investigation elucidates the growing number of breast cancer diagnoses in extremely old women (≥90 years) in a single institution in 2000s.MATERIALS AND METHODS: The database of Yale University Department of Pathology was searched for the terms: "breast carcinoma," "age ≥90" for the past 15 years. Clinicopathologic features of the cases that fit the...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
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