Extracorporeal membrane oxygenation improves outcomes of accidental hypothermia without vital signs: a nationwide observational study

Patients with accidental hypothermia without vital signs increasingly receive venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, there is limited knowledge regarding the efficacy of this advanced rewarming method. We aimed to determine whether VA-ECMO improved outcomes in patients with accidental hypothermia without vital signs, using a large nationwide inpatient database in Japan.
Source: Resuscitation - Category: Emergency Medicine Authors: Tags: Clinical paper Source Type: research

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More patients in arrest with nonshockable rhythms survived with favorable neurologic outcomes if they received moderate therapeutic hypothermia rather than targeted normothermia in a randomized trial.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news
Journal of Perinatology, Published online: 15 October 2019; doi:10.1038/s41372-019-0533-4Opioid and benzodiazepine use during therapeutic hypothermia in encephalopathic neonates
Source: Journal of Perinatology - Category: Perinatology & Neonatology Authors: Source Type: research
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
(Natural News) Hypothermia is a deadly condition that develops in cold temperatures. Preppers must know how to prevent it from happening in the first place – and how to treat it. When a person’s core body temperature drops below 95 F (35 C), he undergoes hypothermia. Dehydration and starvation increase the risk of the condition....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Conclusions: Phosphorylated hexa-acyl disaccharides significantly augment resistance against clinically relevant Gram-negative and Gram-positive infections via enhanced leukocyte recruitment, phagocytosis, and respiratory burst functions of innate leukocytes. Improved antimicrobial protection persists for up to 10 days and is partially mediated through toll-like receptor 4.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research
This study was designed to investigate the effect of an acute intraperitoneal (i.p.) administration of JWH-018-R compounds (0.01-6 mg/kg) on sensorimotor functions in mice and to compare them to those caused by the reference compound JWH-018 and Δ9-THC. A well validated battery of behavioral tests was used to investigate the effects of these synthetic cannabinoids on the visual, auditory and tactile responses in mice, while the pre-pulse inhibition (PPI) test was used to investigate their effect on sensorimotor gating. The effect of the synthetic cannabinoids on spontaneous locomotion was also measured by a vi...
Source: Neurotoxicology - Category: Neurology Authors: Tags: Neurotoxicology Source Type: research
Publication date: Available online 8 October 2019Source: Journal of the Saudi Heart AssociationAuthor(s): Jayavelan Ramkumar, Girish Gopinathan, Karthick Kavin, Ramkumar Shanmugasundaram, George Miller Stephen, Annie Caroline Pragasam, Periyasamy ThangavelAbstractAims and objectiveThe primary objective was to study the effects of cardiopulmonary bypass (CPB) perfusion temperature on renal function parameters (Serum creatinine, Creatinine clearance, Urine Albumin, Urine Protein and Urine Albumin Creatinine Ratio).The secondary objective was to detect renal complications of CPB.Materials and MethodsIt is a prospective longit...
Source: Journal of the Saudi Heart Association - Category: Cardiology Source Type: research
Authors: Martins RM, Teodoro JS, Furtado E, Oliveira RC, Tralhão JG, Rolo AP, Palmeira CM Abstract The organ preservation paradigm has changed following the development of new ways to preserve organs. The use of machine perfusion to preserve organs appears to have several advantages compared with conventional static cold storage. For liver transplants, the temperature control provided by machine perfusion improves organ preservation. In this experimental study, we measured the effects of different temperatures on mitochondrial bioenergetics during the reperfusion phase. An experimental model of ex-vivo liver...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
In this study, we combined computational kinetic modeling and in vitro experimentation to investigate the effects of multifactorial coagulopathy on thrombin, the central enzyme in the coagulation system. METHODS: We measured thrombin generation in platelet-poor plasma from 10 healthy volunteers using the calibrated automated thrombogram assay (CAT). We considered 3 temperature levels (31°C, 34°C, and 37°C), 3 pH levels (6.9, 7.1, and 7.4), and 3 degrees of dilution with normal saline (no dilution, 3-fold dilution, and 5-fold dilution). We measured thrombin-generation time courses for all possible combinati...
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
We report the anaesthetic management of left thoracoscopic sympathectomy in a 5-year-old child with LQTS and epicardial pacemaker in situ. It is very challenging to isolate the lung on one hand and prevent the predisposition to torsadogenic potential on the other.
Source: Indian Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
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