Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review

ABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENTRAL) from inception to April 2018; references from included papers were also searched. The following keywords were used: lubricants OR artificial tears OR artificial tears, lubricants AND dry eye OR dry eye syndrome OR syndromes, dry eye OR dry eyes. Among the 2028 electronic search results, 29 full papers were retrieved and four were considered relevant. The number of participants from these studies ranged from 15 to 76. Meta-analysis was possible for the following outcomes: score of symptoms according to the Ocular Surface Disease Index - Allergan (OSDI), tear secretion rate using the Schirmer test, tear evaporation rate using the tear film breakup time test, burning, foreign body sensation, and photophobia. No statistically significant difference was observed between the two groups, and no side effects were attributed to the interventions. Evidence proving that preservative-free artificial tears are more effective than preserved artificial tears is lacking.RESUMO Esta revis ão sistemática teve como objetivo avaliar a eficácia do uso de lágrimas artificiais sem conservantes em comparação com lubrificantes preservados no tratamento do olho...
Source: Arquivos Brasileiros de Oftalmologia - Category: Opthalmology Source Type: research

Related Links:

Abstract Humoral immunological defects are frequent and important causes of hypogammaglobulinemia, leading to recurrent infections, autoimmunity, allergies, and neoplasias. Usually, its onset occurs in childhood or during the second and third decades of life; however, the diagnosis is made, on average, 6 to 7 years afterwards. As a consequence, antibody defects can lead to sequelae. Here we describe the clinical-laboratory characteristics, treatment, and prognoses of patients with hypogammaglobulinemia. An observational, cross-sectional, and retrospective study of patients attending the recently established outpat...
Source: Braz J Med Biol Res - Category: Research Authors: Tags: Braz J Med Biol Res Source Type: research
People at high risk for serious flu complications are those with conditions such as asthma, chronic lung disease, diabetes, heart disease, morbid obesity, or adults aged 65 years or older.FDA Approvals
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Infectious Diseases News Alert Source Type: news
Authors: Lombardi C, Cottini M, Passalacqua G PMID: 30039694 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Authors: Woźniewicz A, Szynkiewicz E, Pałgan K, Graczyk M, Dowbór-Dzwonka A, Bartuzi Z Abstract Introduction: The level of fear of hymenoptera associated with stinging or envenomation may depend on situational factors and on trait anxiety characteristic of each patient. Aim: To assess the relationship between fear of stinging insects on the one hand and state anxiety and trait anxiety on the other in a group of patients with hymenoptera venom allergy. Material and methods: The study was conducted by the Department of Allergy, Clinical Immunology and Internal Diseases, Dr J. Biziel University Hospit...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
We ’ve all read about the potential for data to transform healthcare by enabling patients to better understand their conditions and engage better in their treatment.  Now a handful of pioneers are starting to demonstrate the potential and to justify some of the hype. Some rapid improvements in outcomes and adherence point the way to a future in which agile pharma teams routinely work with ever more real-time, real-world data to rapidly and iteratively improve patient insights and outcomes. In the era in which payments will increasingly be tied to results, such innovations should be of huge value, and w...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
This article summarizes available data on the use of bilastine in the treatment of allergic disorders in different age groups, including younger and older adults, and school-age children and adolescents. Methods: A PubMed literature search ("bilastine") was conducted to 25 February 2019. Additional literature known to the authors and identified from the reference lists of cited publications was included. Results: Bilastine is administered orally at a dose of 20 mg once daily in adults and adolescents aged ≥12 years and 10 mg once daily in children aged 6 to
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
By Sandee LaMotte, CNN (CNN) — Toxic heavy metals damaging to your baby’s brain development are likely in the baby food you are feeding your infant, according to a new investigation published Thursday. Tests of 168 baby foods from major manufacturers in the US found 95% contained lead, 73% contained arsenic, 75% contained cadmium and 32% contained mercury. One fourth of the foods contained all four heavy metals. One in five baby foods tested had over 10 times the 1-ppb limit of lead endorsed by public health advocates, although experts agree that no level of lead is safe. The results mimicked a previous&nb...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Consumer Featured Health News Syndicated CBSN Boston CNN Source Type: news
Updated Date: Thu, 17 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Updated Date: Thu, 17 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Updated Date: Thu, 17 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
More News: Allergy | Databases & Libraries | Eyes | Opthalmology | Statistics | Study