Training artificial neural networks directly on the concordance index for censored data using genetic algorithms

Conclusions: We have found empirical evidence that ensembles of ANN models can be optimized directly on the c-index. Comparison with a Cox model indicates that near identical performance is achieved on a real cancer data set while on a non-linear data set the ANN model is clearly superior.

Source: Artificial Intelligence in Medicine - April 12, 2013 Category: Bioinformatics Authors: Jonas Kalderstam, Patrik Edén, Pär-Ola Bendahl, Carina Strand, Mårten Fernö, Mattias Ohlsson Tags: Research Articles Source Type: research