Distribution of Neisseria meningitidis serogroup B (NmB) vaccine antigens in meningococcal disease causing isolates in the United States during 2009-2014, prior to NmB vaccine licensure

Neisseria meningiditis (Nm) is a commensal bacterium that can cause severe infections which are collectively known as meningococcal disease. Effective vaccines are important for disease control and prevention.1 During 2009-2014, 4109 cases of meningococcal disease were reported in the United States, with serogroups B, C and Y accounting for the majority of cases.2,3 Quadrivalent meningococcal polysaccharide conjugate vaccine (MenACWY) was recommended for adolescents aged 11 –18 years in the United States in 2005 to protect against disease caused by Nm serogroups A, C, W and Y.
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research