Impact of polyvascular disease on clinical outcomes in patients undergoing coronary revascularization: An observation from the CREDO-Kyoto Registry Cohort-2

Abstract: Objective: Patients with coronary artery disease (CAD) often have prior stroke or concomitant extra-cardiac vascular disease (EVD) such as cerebral, aortic, or peripheral vascular disease. However, clinical outcomes after coronary revascularization in patients with polyvascular disease have not been fully elucidated.Methods: Among 15,263 patients undergoing first coronary revascularization enrolled in the CREDO-Kyoto registry Cohort-2 from January 2005 to December 2007, there were 1443 patients with prior stroke (stroke + CAD group), 974 patients with EVD (EVD + CAD group), 253 patients with both prior stroke and EVD (stroke/EVD/CAD group) and 12,593 patients with neither prior stroke nor EVD (CAD alone group [reference]).Results: The cumulative incidence of major adverse cardiovascular events (MACE: composite of cardiovascular death, myocardial infarction and stroke) through 3 years was significantly higher in patients with polyvascular disease compared with reference patients (19.9% in the stroke + CAD group, 18.5% in the EVD + CAD group, 20.1% in the stroke/EVD/CAD group, and 11.2% in the CAD alone group, P 

Source: Atherosclerosis - April 29, 2013 Category: Cardiology Authors: Yuko Morikami, Masahiro Natsuaki, Takeshi Morimoto, Koh Ono, Yoshihisa Nakagawa, Yutaka Furukawa, Ryuzo Sakata, Masaki Aota, Yukikatsu Okada, Masahiko Onoe, Michio Kawasuji, Takaaki Koshiji, Hiroyuki Nakajima, Junichiro Nishizawa, Kazuo Yamanaka, Hiroyuki Tags: Intervention Source Type: research