CSF orexin-A levels after rituximab treatment in recent onset narcolepsy type 1

A 28-year-old man with narcolepsy type 1 (NT1) was referred due to excessive daytime sleepiness starting 5 months earlier, and 2 months prior to his admission, he had 1 to 3 daily cataplexies related to laughter, anger, and surprise, leading to a loss of muscle tone in the face, neck, and legs. Inquiries with Epworth Sleepiness Scale (ESS) was initially 21 of 24 points. Prior to admission, his medical history was insignificant, and physical examination did not show any neurologic deficits.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Tags: Autoimmune diseases, Narcolepsy Clinical/Scientific Notes Source Type: research