Sodium butyrate alleviates high-glucose-induced renal glomerular endothelial cells damage via inhibiting pyroptosis.

In conclusion, NaB could ameliorate high-glucose induced GECs via caspase1-GSDMD canonical pyroptosis pathway; and NF-κB/IκB-α signaling pathway was involved in it. PMID: 31473434 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31473434?dopt=Abstract

Source: International Immunopharmacology - August 28, 2019 Category: Allergy & Immunology Authors: Gu J, Huang W, Zhang W, Zhao T, Gao C, Gan W, Rao M, Chen Q, Guo M, Xu Y, Xu YH Tags: Int Immunopharmacol Source Type: research