Association between circulating 25 ‐hydroxyvitamin D and systemic lupus erythematosus: A systematic review and meta‐analysis

ConclusionsCompared with healthy controls, 25(OH)D levels are significantly lower in SLE patients, which is influenced by disease activity, ethnicity, seasons and vitamin D supplement; no matter the change of age, diseases duration and therapy of corticosteroid or immunosuppressive or neither, 25(OH)D levels are significantly decreased in SLE patients; the deficiency, insufficiency and sufficiency of vitamin D could significantly elevate, slightly decrease, and significantly decrease SLE risk, respectively; and 25(OH)D levels inversely correlate with SLEDAI.

Source: International Journal of Rheumatic Diseases - August 29, 2019 Category: Rheumatology Authors: Shi ‐Yang Guan, Hong‐Yan Cai, Peng Wang, Tian‐Tian Lv, Li‐Na Liu, Yan‐Mei Mao, Chan‐Na Zhao, Qian Wu, Yi‐Lin Dan, Napoleon Bellua Sam, De‐Guang Wang, Hai‐Feng Pan Tags: REVIEW Source Type: research