Renal cell carcinoma: predicting RUNX3 methylation level and its consequences on survival with CT features

ConclusionsHigher levels of RUNX3 methylation are associated with shorter survival in ccRCC patients. And presence of intratumoral vascularity, ill-defined margin, and left side tumor were significant independent predictors of high methylation level of RUNX3 gene.Key Points•RUNX3 methylation level is negatively associated with overall survival in ccRCC patients.•Presence of intratumoral vascularity, ill-defined margin, and left side tumor were significant independent predictors of high methylation level of RUNX3 gene.
Source: European Radiology - Category: Radiology Source Type: research