Comparative genomic analyses of Chinese serogroup W ST-11 complex Neisseria meningitidis isolates

Neisseria meningitidis is one of the more important pathogens of severe bacterial meningitis and septicaemia and can be classified into 12 different serogroups based on differences in the polysaccharide capsules. Serogroups A, B, C, W, X and Y cause almost all cases of invasive meningococcal disease (IMD).1,2 Vaccination using serogroup-specific polysaccharide or conjugate vaccines is the most effective means of prevention of IMD. Different serogroup distributions across different countries have led to different vaccination programmes and strategies.

Source: Journal of Infection - August 28, 2019 Category: Infectious Diseases Authors: Bingqing Zhu, Jay Lucidarme, Xilian Bai, Pengbo Guo, Aiyu Zhang, Ray Borrow, Wanying Gao, Li Xu, Yuan Gao, Zhujun Shao Source Type: research