The Guardian view on the menopause at work: a healthy conversation | Editorial

From new employee entitlements to soap opera storylines, older women ’s health needs a bigger profileConnected as it is with ageing, it is not surprising that the menopause has a bad reputation. Even for women who have generally found their periods to be a nuisance, the cessation of the monthly cycle of egg production often comes as a shock. As well as the psychological impact of what used to euphemistically be called “the change”, the menopause brings with it symptoms for which a lot of women find themselves alarmingly unprepared – asmany readers told us when we invited them to share their stories.These symptoms include the heavy or irregular bleeding that often precedes the cessation of menstruation, hot flushes and night sweats, an increased risk of osteoporosis (brittle bones), disrupted sleep, anxiety, vaginal dryness and reduced sex drive. Given all this, and the fact that millions of women are going through the menopause at any one time (around 1 million women in the UK take hormone replacement therapy, although four in five do not medicate), it is remarkable the extent to which the taboo surrounding the menopause remains untouched. Even as other aspects of female reproductive health have become more widely discussed, the menopause has been stuck on the shelf.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Menopause Health Women Television industry Feminism World news Science Work & careers Guardian Careers Money Media Society Life and style Source Type: news

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This study aims to investigate the current status of FI among patients with severe neurological conditions and to further determine the correlation between FI and their poor prognosis. Methods: A retrospective analysis of the medical data of 58 patients who stayed for more than 3 days in the neurointensive care unit (NICU) of the Department of Neurology of the First Affiliated Hospital of Chongqing Medical University between January 2017 and December 2017, was carried out. These patients' diagnoses included five categories (Stroke, Paroxysmal disease, Peripheral nerve disease, Central nervous system infection, Other diseas...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
CONCLUSIONS: The rate of overall complications after TRUS was low. The most common complications requiring emergency attendances and hospitalisations were gross haematuria and acute urinary retention, respectively. Prostate volume>48 cc increased the risk of post-biopsy urinary retention. PMID: 31601774 [PubMed - as supplied by publisher]
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
Authors: Gong M, Zhao B, He X, Gu J, Chen G Abstract The aim of the present study was to investigate whether the rescue of thrombolysis with the recombinant tissue plasminogen activator (rt-PA) alteplase was an effective and safe therapeutic option in patients who did not respond to urokinase. Between February 2016 and February 2017, 26 patients with deep venous thrombosis (DVT) underwent rescue thrombolysis with alteplase. Unsuccessful thrombolysis with urokinase was defined as a lack of improvement in the degree of thrombotic removal with a lysis rate 3 million units of total urokinase, or>7 days infusion dura...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang H, Ding W, Ji F, Wu D Abstract The present study aimed to investigate bone morphogenetic protein (BMP)-2 and microRNA (miR)-410 expression and the mechanism of regulation in serum and CD14+ peripheral blood mononuclear cells (PBMCs) from postmenopausal osteoporosis patients and model mice. A total of 26 patients with postmenopausal osteoporosis were included in the experimental group and 29 age-matched healthy subjects were included in the control group. A total of 60 mice were divided into sham and ovariectomized (OVX) groups. Following surgery, 28 mice remained in the sham and 25 mice remained in O...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Conclusions: There is thin evidence that diaries and exercise programs have a positive effective on mental outcomes. Despite outcomes favoring the intervention group, other commonly used nonpharmacologic interventions in daily ICU practice are not supported by conclusive evidence from this meta-analysis. To improve recovery programs for ICU survivors, more evidence is needed from robust intervention studies using standardized outcomes.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Review Articles Source Type: research
Conclusions: In spite of the lack of high-quality evidence, recommendations for pain management at the end-of-life in the ICU are homogeneous and are justified by ethical principles and agreement among experts. Considering the growing demand for the involvement of palliative care teams in the management of the dying patients in the ICU, there is a need to clearly define their early involvement and to further develop comprehensive evidence-based pain management strategies. Based on the study findings, we propose a management algorithm to improve the overall care of dying critically ill patients.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Review Articles Source Type: research
Conclusions: In children supported by extracorporeal membrane oxygenation, chest tube bleeding above 60 mL/kg/d was independently associated with worse clinical outcome. Low fibrinogen was independently associated with chest tube bleeding, whereas platelet count and hemostatic tests were not. Further research is needed to evaluate if interventions to prevent or stop chest tube bleeding influence the clinical outcome.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research
Authors: Lara-Ruiz J, Kauzor K, Nakhala M, Banuelos D, Woo E, Apostolova LG, Razani J Abstract Sixty patients and their caregivers participated in this study. Patients completed activities of daily living tasks and several neuropsychological tests assessing memory, abstract reasoning, and language. Caregivers completed self-report measures assessing caregiver burden and psychological distress. Results revealed that the mAD caregivers endorsed greater physical burden and feelings of missing out on life compared to MCI caregivers. The mAD caregivers indicated greater depression and anxiety relative to MCI caregivers....
Source: GeroPsych - Category: Geriatrics Tags: GeroPsych (Bern) Source Type: research
AbstractPurposeVulvovaginal atrophy (VVA) is a commonly reported issue among breast cancer patients, and its aetiology is multifactorial. Treatment is difficult in these women, particularly because the use of oestrogens has traditionally been discouraged. Vaginal laser treatment has been reported to improve symptoms. We aimed to assess the impact on symptoms and sexual function of vaginal laser in women with early breast cancer (EBC).MethodsWe performed a single-arm investigator initiated pilot study of female EBC patients with symptomatic VVA. A total of 3 vaginal laser treatments were administered 4  weeks apart. Qu...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Authors: Gohil A, Eugster E Abstract The somatotropic axis is intricately involved in normal sleep, as evidenced by the fact that hypothalamic growth hormone-releasing hormone (GHRH) has sleep promoting effects and pituitary growth hormone (GH) release is strongly associated with slow-wave sleep (SWS). Abnormalities in the somatotropic axis, such as GH deficiency of hypothalamic or pituitary origin, result in an alteration of normal sleep patterns which may explain the fatigue reported in these individuals. Sleep disorders such as narcolepsy, in which individuals abnormally enter rapid eye movement (REM) sleep at s...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
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