Long-Term Vitamin K Antagonists and Cancer Risk: A Systematic Review and Meta-Analysis

Objectives: Vitamin K antagonists (VKAs) remain one of the most commonly used anticoagulation therapies. The potential anticancer effect of long-term use of VKAs has been a matter of debate with conflicting results. Our goal was to perform a systematic review and meta-analysis examining the association between long-term VKAs use and cancer risk. Methods: Systematic searches of multiple major databases were performed from inception until January 2018. We included studies of adults that compared incidence of any cancer between ≥6 months use of VKAs (long-term group) and
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Review Articles Source Type: research