MiR ‐497‐5p inhibits cell proliferation and metastasis in hepatocellular carcinoma by targeting insulin‐like growth factor 1

ConclusionOur study suggested that miR ‐497‐5p regulates HCC cell survival, partially through downregulation of IGF1. Therefore, the miR‐497‐5p/IGF1 axis might serve as a novel therapeutic target in patients with HCC.

Source: Molecular Genetics & Genomic Medicine - August 22, 2019 Category: Genetics & Stem Cells Authors: Guo ‐shu Xu, Zi‐wei Li, Zhi‐Ping Huang, F. Charles Brunicardi, Fu Jia, Chao Song, Hai‐jian Zou, Rui‐fen Sun Tags: ORIGINAL ARTICLE Source Type: research