Implications of nanotechnology for the treatment of cancer: Recent advances

Publication date: Available online 22 August 2019Source: Seminars in Cancer BiologyAuthor(s): Sergey G. Klochkov, Margarita E. Neganova, Vladimir N. Nikolenko, Kuo Chen, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch AlievAbstractThe use of nanoparticles dramatically increases the safety and efficacy of the most common anticancer drugs. The main advantages of nano-drugs and delivery systems based on nano-technology are effective targeting, delayed release, increased half-life, and less systemic toxicity. The use of nano-carriers has led to significant improvements in drug delivery to targets compared with traditional administration of these drugs. In this review, the main tendencies in nano-drug formulations as well as factors limiting their use in clinical settings are discussed. Additionally, the current status of approved nano-drugs for cancer treatment is reviewed.
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research