Inclusion of heart substructures in the optimization process of volumetric modulated arc therapy techniques may reduce the risk of heart disease in Hodgkin ’s lymphoma patients
The risk-adapted combination of brief chemotherapy followed by radiation therapy (RT), nowadays represents the therapeutic golden standard for early stage Hodgkin lymphoma (HL) [1]. Nonetheless, the role of radiation is still debated, with some concerns for late toxicity (second malignancies, heart disease). Current RT protocols combine limited radiation volumes (involved site or involved nodal radiotherapy, ISRT/INRT) with advanced planning and delivery techniques, such as intensity modulated RT (IMRT), tomotherapy and proton therapy.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Mario Levis, Andrea Riccardo Filippi, Christian Fiandra, Viola De Luca, Sara Bartoncini, Dwayne Vella, Riccardo Ragona, Umberto Ricardi Tags: Original Article Source Type: research
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