Inclusion of heart substructures in the optimization process of volumetric modulated arc therapy techniques may reduce the risk of heart disease in Hodgkin ’s lymphoma patients

The risk-adapted combination of brief chemotherapy followed by radiation therapy (RT), nowadays represents the therapeutic golden standard for early stage Hodgkin lymphoma (HL) [1]. Nonetheless, the role of radiation is still debated, with some concerns for late toxicity (second malignancies, heart disease). Current RT protocols combine limited radiation volumes (involved site or involved nodal radiotherapy, ISRT/INRT) with advanced planning and delivery techniques, such as intensity modulated RT (IMRT), tomotherapy and proton therapy.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research