Severe nail psoriasis managed succesflly with apremilast

Psoriasis is a chronic, systemic, inflammatory disease involving skin, nails, and joints. Nail psoriasis may lead to many difficulties in daily activities including work and impairment in quality of life and may also be the cause of severe pain, anxiety and depression. A 66-year-old woman with a history of seronegative arthritis receiving methotrexate presented with severe ungual dystrophy affecting all 20 nails. Clinical examination revealed subungual hyperkeratosis, salmon patches, periungual erythema, onycholysis and nail crumbling.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research