Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells.
In conclusion, these results suggest that increased Bach1 contributes to aging-related loss of electrophile-enhanced Nrf2 signaling.
PMID: 31422075 [PubMed - as supplied by publisher]
Source: Archives of Biochemistry and Biophysics - Category: Biochemistry Authors: Zhang H, Zhou L, Davies KJA, Forman HJ Tags: Arch Biochem Biophys Source Type: research