A 2-year multicenter, observational, prospective, cohort study on extracorporeal CO 2 removal in a large metropolis area

ConclusionsBased on a registry, we report a low rate of ECCO2R device utilization, mainly in severe COPD and ARDS patients. Physiological efficacy was confirmed in these two populations. We confirmed safety concerns such as hemolysis, bleeding, and thrombosis, with different profiles between the devices. Such results could help to design future studies aiming to enhance safety, to demonstrate a still-lacking strong clinical benefit of ECCO2R, and to guide the choice between different devices.Trial registrationClinicalTrials.gov: Identifier: NCT02965079 retrospectively registeredhttps://clinicaltrials.gov/ct2/show/NCT02965079
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research